Transcriptomic and ultrastructural responses to Amiodarone–Itraconazole in naturally benznidazole-resistant and -susceptible Trypanosoma cruzi strains

• Stivenn Gutiérrez,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft

  Affiliation Centro de Investigaciones en Microbiología y Biotecnología-UR (CIMBIUR), School of Sciences and Engineering, Universidad del Rosario, Bogotá, Colombia

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• Carlos Ospina,

  Roles Formal analysis, Investigation, Methodology, Resources, Writing – review & editing

  Affiliation Centro de Investigaciones en Microbiología y Biotecnología-UR (CIMBIUR), School of Sciences and Engineering, Universidad del Rosario, Bogotá, Colombia

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• Tatiana Cáceres,

  Roles Investigation, Methodology, Resources, Writing – review & editing

  Affiliation Centro de Investigaciones en Microbiología y Biotecnología-UR (CIMBIUR), School of Sciences and Engineering, Universidad del Rosario, Bogotá, Colombia

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• Luz Helena Patiño,

  Roles Investigation, Methodology, Resources, Writing – review & editing

  Affiliation Centro de Investigaciones en Microbiología y Biotecnología-UR (CIMBIUR), School of Sciences and Engineering, Universidad del Rosario, Bogotá, Colombia

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• Alberto Paniz-Mondolfi ,

  Roles Conceptualization, Investigation, Methodology, Writing – review & editing

  ¶‡ These authors are senior authors on this work.

  Affiliation Molecular Microbiology Laboratory, Department of Pathology, Molecular and Cell- based Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America

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• Juan David Ramírez

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft

  * E-mail: jramirezgonzalez@usf.edu

  ¶‡ These authors are senior authors on this work.

  Affiliations Centro de Investigaciones en Microbiología y Biotecnología-UR (CIMBIUR), School of Sciences and Engineering, Universidad del Rosario, Bogotá, Colombia, Center for Global Health and Interdisciplinary Research, USF Genomics Program, Department of Global, Environmental and Genomic Health Sciences, College of Public Health, University of South Florida, Tampa, Florida, United States of America

  https://orcid.org/0000-0002-1344-9312

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