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Open Access
Peer-reviewed
Research Article
Severe visceral leishmaniasis in Ethiopia: Outcomes, co-infections and mortality in a prospective real-world cohort
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Eleni Ayele ,
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Writing – original draft, Writing – review & editing
* E-mail: eleniayele2@gmail.com
Affiliations Department of Internal Medicine, University of Gondar, Gondar, Ethiopia, Leishmaniasis Research and Treatment Center, University of Gondar, Gondar, Ethiopia
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Saskia van Henten,
Roles Conceptualization, Data curation, Methodology, Project administration, Supervision, Writing – review & editing
Affiliation Department of Clinical Sciences, Institute of Tropical Medicine Antwerp, Antwerp, Belgium
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Desalew Getahun Ayalew,
Roles Investigation, Writing – review & editing
Affiliation Department of Internal Medicine, University of Gondar, Gondar, Ethiopia
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Saba Atnafu,
Roles Investigation, Writing – review & editing
Affiliation Leishmaniasis Research and Treatment Center, University of Gondar, Gondar, Ethiopia
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Asnakew Engidaw Mereed,
Roles Investigation, Writing – review & editing
Affiliation Leishmaniasis Research and Treatment Center, University of Gondar, Gondar, Ethiopia
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Hana Yohannes,
Roles Data curation, Investigation, Writing – review & editing
Affiliation Department of Immunology, University of Gondar, Gondar, Ethiopia
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Tigist Mekonnen,
Roles Investigation, Writing – review & editing
Affiliation Leishmaniasis Research and Treatment Center, University of Gondar, Gondar, Ethiopia
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Tadfe Bogale,
Roles Data curation, Project administration, Writing – review & editing
Affiliation Leishmaniasis Research and Treatment Center, University of Gondar, Gondar, Ethiopia
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Aman Mossa,
Roles Investigation, Writing – review & editing
Affiliation Leishmaniasis Research and Treatment Center, University of Gondar, Gondar, Ethiopia
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Gebrehiwot Lema Legese,
Roles Investigation, Writing – review & editing
Affiliation Department of Internal Medicine, University of Gondar, Gondar, Ethiopia
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Jemal Yasin,
Roles Methodology, Writing – review & editing
Affiliation Leishmaniasis Research and Treatment Center, University of Gondar, Gondar, Ethiopia
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Nicole Berens-Riha,
Roles Data curation, Formal analysis, Visualization, Writing – review & editing
Affiliation Department of Clinical Sciences, Institute of Tropical Medicine Antwerp, Antwerp, Belgium
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Thao-Thy Pham,
Roles Investigation, Writing – review & editing
Affiliation Department of Clinical Sciences, Institute of Tropical Medicine Antwerp, Antwerp, Belgium
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Carl Boodman,
Roles Writing – review & editing
Affiliations Department of Clinical Sciences, Institute of Tropical Medicine Antwerp, Antwerp, Belgium, Department of Medical Sciences, University of Antwerp, Antwerp, Belgium
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Annelies Mondelaers,
Roles Methodology, Writing – review & editing
Affiliations Department of Clinical Sciences, Institute of Tropical Medicine Antwerp, Antwerp, Belgium, Department of Internal Medicine, Infectious Diseases and Tropical Medicine, Antwerp University Hospital, Antwerp, Belgium
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Wim J. Adriaensen,
Roles Methodology, Writing – review & editing
Affiliation Department of Clinical Sciences, Institute of Tropical Medicine Antwerp, Antwerp, Belgium
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Saïd Abdellati,
Roles Investigation, Writing – review & editing
Affiliation Department of Clinical Sciences, Institute of Tropical Medicine Antwerp, Antwerp, Belgium
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Ermias Diro,
Roles Methodology, Writing – review & editing
Affiliation Department General Internal Medicine, University of Washington, Seattle, Washington, United States of America
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Rezika Mohammed,
Roles Conceptualization, Writing – review & editing
Affiliation Leishmaniasis Research and Treatment Center, University of Gondar, Gondar, Ethiopia
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Fabiana Alves,
Roles Supervision, Writing – review & editing
Affiliation Drugs for Neglected Disease Initiative, Geneva, Switzerland
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Mezgebu Silamsaw Asres,
Roles Investigation, Writing – review & editing
Affiliations Department of Internal Medicine, University of Gondar, Gondar, Ethiopia, Leishmaniasis Research and Treatment Center, University of Gondar, Gondar, Ethiopia
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Myrthe Pareyn,
Roles Funding acquisition, Writing – review & editing
Affiliation Department of Clinical Sciences, Institute of Tropical Medicine Antwerp, Antwerp, Belgium
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Mekibib Kassa,
Roles Investigation, Writing – review & editing
Affiliation Leishmaniasis Research and Treatment Center, University of Gondar, Gondar, Ethiopia
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Johan van Griensven
Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing
Affiliation Department of Clinical Sciences, Institute of Tropical Medicine Antwerp, Antwerp, Belgium
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Severe visceral leishmaniasis in Ethiopia: Outcomes, co-infections and mortality in a prospective real-world cohort
- Eleni Ayele,
- Saskia van Henten,
- Desalew Getahun Ayalew,
- Saba Atnafu,
- Asnakew Engidaw Mereed,
- Hana Yohannes,
- Tigist Mekonnen,
- Tadfe Bogale,
- Aman Mossa,
- Gebrehiwot Lema Legese
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- Published: June 5, 2026
- https://doi.org/10.1371/journal.pntd.0013878