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Open Access
Peer-reviewed
Research Article
Neurological manifestations and MMP8 as a prognostic biomarker in severe fever with thrombocytopenia syndrome
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Qi Xia ,
Contributed equally to this work with: Qi Xia, Ziling Cheng
Roles Data curation, Formal analysis, Funding acquisition, Project administration, Resources, Writing – original draft
Affiliation State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
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Ziling Cheng ,
Contributed equally to this work with: Qi Xia, Ziling Cheng
Roles Data curation, Formal analysis, Resources, Writing – original draft
Affiliation State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
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Yi Zhang,
Roles Resources
Affiliation Department of Laboratory Medicine, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
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Haolin Song,
Roles Resources
Affiliation State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
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Bei Jia,
Roles Data curation
Affiliation Department of Infectious Diseases, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu, China
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Lingtong Huang,
Roles Methodology
Affiliation Department of Critical Care Units, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
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Qiuhong Liu,
Roles Resources
Affiliation State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
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Qing Zhao,
Roles Resources
Affiliation State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
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Jie Li ,
Roles Resources, Writing – review & editing
* E-mail: lijier@nju.edu.cn (JL); wangjie_lethe@zju.edu.cn (JW); zjuwuwei@zju.edu.cn (WW)
Affiliation Department of Infectious Diseases, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu, China
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Jie Wang ,
Roles Conceptualization, Methodology, Project administration, Writing – original draft, Writing – review & editing
* E-mail: lijier@nju.edu.cn (JL); wangjie_lethe@zju.edu.cn (JW); zjuwuwei@zju.edu.cn (WW)
Affiliation State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
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Wei Wu
Roles Conceptualization, Data curation, Funding acquisition, Methodology, Project administration, Writing – review & editing
* E-mail: lijier@nju.edu.cn (JL); wangjie_lethe@zju.edu.cn (JW); zjuwuwei@zju.edu.cn (WW)
Affiliation State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
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Neurological manifestations and MMP8 as a prognostic biomarker in severe fever with thrombocytopenia syndrome
- Qi Xia,
- Ziling Cheng,
- Yi Zhang,
- Haolin Song,
- Bei Jia,
- Lingtong Huang,
- Qiuhong Liu,
- Qing Zhao,
- Jie Li,
- Jie Wang
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- Published: December 26, 2025
- https://doi.org/10.1371/journal.pntd.0013875