In vitro and in vivo efficacy of the antimycobacterial molecule SQ109 against the human pathogenic fungus, Cryptococcus neoformans

• Nour M. Alkashef,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing

  Affiliations Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, United States of America, Center for One Health Research, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, United States of America

  https://orcid.org/0009-0008-0632-3747

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• Ehab A. Salama,

  Roles Writing – review & editing

  Affiliations Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, United States of America, Center for One Health Research, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, United States of America

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• Ramu Anandakrishnan,

  Roles Formal analysis, Investigation, Visualization, Writing – original draft

  Affiliations Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, United States of America, Department of Biomedical Sciences, Edward Via College of Osteopathic Medicine (VCOM), Blacksburg, Virginia, United States of America

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• Tony R. Hazbun,

  Roles Resources, Writing – review & editing

  Affiliations Purdue Institute for Cancer Research, Purdue University, West Lafayette, Indiana, United States of America, Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, Indiana, United States of America

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• Micah V. Hoernig,

  Roles Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Biochemistry, Virginia Polytechnic Institute and State University (Virginia Tech), Blacksburg, Virginia, United States of America

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• Anne M. Brown,

  Roles Investigation, Writing – review & editing

  Affiliations Department of Biochemistry, Virginia Polytechnic Institute and State University (Virginia Tech), Blacksburg, Virginia, United States of America, Center for Emerging, Zoonotic, and Arthropod-borne Pathogens, Virginia Polytechnic Institute and State University (Virginia Tech), Blacksburg, Virginia, United States of America, Research & Informatics and Department of Biochemistry, Virginia Polytechnic Institute and State University (Virginia Tech), Blacksburg, Virginia, United States of America

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• Christopher B. Lawrence,

  Roles Writing – review & editing

  Affiliations Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, United States of America, Center for One Health Research, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, United States of America

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• Mohamed N. Seleem

  Roles Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing

  * E-mail: seleem@vt.edu

  Affiliations Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, United States of America, Center for One Health Research, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, United States of America

  https://orcid.org/0000-0003-0939-0458

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