Functional dynamics between resident transcriptionally active microbes (TAMs) and host genes underlie Dengue severity

Pallawi Kumari; Priti Devi; Basudha Banerjee; Bansidhar Tarai; Sandeep Budhiraja; Tav Pritesh Sethi; Rajesh Pandey

doi:10.1371/journal.pntd.0013836

Loading metrics

Open Access

Peer-reviewed

Research Article

Functional dynamics between resident transcriptionally active microbes (TAMs) and host genes underlie Dengue severity

Pallawi Kumari,

Roles Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft

Affiliations Division of Infectious Disease Biology, INtegrative GENomics of Host-PathogEn (INGEN-HOPE) laboratory, CSIR-Institute of Genomics and Integrative Biology (CSIR-IGIB), Mall Road, Delhi, India, Indraprastha Institute of Information Technology (IIIT) Delhi, New Delhi, India
⨯
Priti Devi,

Roles Data curation, Investigation, Methodology, Visualization, Writing – original draft

Affiliation Division of Infectious Disease Biology, INtegrative GENomics of Host-PathogEn (INGEN-HOPE) laboratory, CSIR-Institute of Genomics and Integrative Biology (CSIR-IGIB), Mall Road, Delhi, India
⨯
Basudha Banerjee,

Roles Methodology, Visualization, Writing – original draft

Affiliation Division of Infectious Disease Biology, INtegrative GENomics of Host-PathogEn (INGEN-HOPE) laboratory, CSIR-Institute of Genomics and Integrative Biology (CSIR-IGIB), Mall Road, Delhi, India
⨯
Bansidhar Tarai,

Roles Resources

Affiliation Max Super Speciality Hospital (A Unit of Devki Devi Foundation), Max Healthcare, Delhi, India
⨯
Sandeep Budhiraja,

Roles Resources

Affiliation Max Super Speciality Hospital (A Unit of Devki Devi Foundation), Max Healthcare, Delhi, India
⨯
Tav Pritesh Sethi ,

Roles Data curation, Project administration, Supervision, Writing – review & editing

* E-mail: rajeshp.igib@csir.res.in

Affiliation Indraprastha Institute of Information Technology (IIIT) Delhi, New Delhi, India
⨯
Rajesh Pandey

Roles Conceptualization, Funding acquisition, Investigation, Project administration, Resources, Supervision, Writing – review & editing

* E-mail: rajeshp.igib@csir.res.in

Affiliations Division of Infectious Disease Biology, INtegrative GENomics of Host-PathogEn (INGEN-HOPE) laboratory, CSIR-Institute of Genomics and Integrative Biology (CSIR-IGIB), Mall Road, Delhi, India, Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India

https://orcid.org/0000-0002-4404-8327

⨯

Functional dynamics between resident transcriptionally active microbes (TAMs) and host genes underlie Dengue severity

Pallawi Kumari,
Priti Devi,
Basudha Banerjee,
Bansidhar Tarai,
Sandeep Budhiraja,
Tav Pritesh Sethi,
Rajesh Pandey

Published: December 19, 2025
https://doi.org/10.1371/journal.pntd.0013836

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Dengue fever
Is the Subject Area "Dengue fever" applicable to this article?

Thanks for your feedback.
Virus effects on host gene expression
Is the Subject Area "Virus effects on host gene expression" applicable to this article?

Thanks for your feedback.
Immune response
Is the Subject Area "Immune response" applicable to this article?

Thanks for your feedback.
Host-pathogen interactions
Is the Subject Area "Host-pathogen interactions" applicable to this article?

Thanks for your feedback.
Microbiome
Is the Subject Area "Microbiome" applicable to this article?

Thanks for your feedback.
RNA sequencing
Is the Subject Area "RNA sequencing" applicable to this article?

Thanks for your feedback.
Dengue virus
Is the Subject Area "Dengue virus" applicable to this article?

Thanks for your feedback.
Microbial taxonomy
Is the Subject Area "Microbial taxonomy" applicable to this article?

Thanks for your feedback.