The phytochemical arbutin exerts potent anti-Toxoplasma effects through activation of cell-autonomous defense mechanisms while attenuating inflammation

• Zhuanzhuan Liu ,

  Contributed equally to this work with: Zhuanzhuan Liu, Yulu Ma

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft

  * E-mail: wangyg@xzhmu.edu.cn (YW); Liouzhuanzhuan12@163.com (ZL)

  Affiliations Jiangsu Key Laboratory of Immunity and Metabolism, Xuzhou Medical University, Xuzhou, China, Laboratory of Infection and Immunity, Department of Pathogenic Biology and Immunology, School of Basic Medical Sciences, Xuzhou Medical University, Xuzhou, China

  https://orcid.org/0000-0002-9453-9714

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• Yulu Ma ,

  Contributed equally to this work with: Zhuanzhuan Liu, Yulu Ma

  Roles Formal analysis, Investigation, Validation

  Affiliations Jiangsu Key Laboratory of Immunity and Metabolism, Xuzhou Medical University, Xuzhou, China, Laboratory of Infection and Immunity, Department of Pathogenic Biology and Immunology, School of Basic Medical Sciences, Xuzhou Medical University, Xuzhou, China

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• Yaoyao Xiang,

  Roles Investigation, Validation

  Affiliations Jiangsu Key Laboratory of Immunity and Metabolism, Xuzhou Medical University, Xuzhou, China, Laboratory of Infection and Immunity, Department of Pathogenic Biology and Immunology, School of Basic Medical Sciences, Xuzhou Medical University, Xuzhou, China

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• Yusi Shen,

  Roles Investigation, Validation

  Affiliations Jiangsu Key Laboratory of Immunity and Metabolism, Xuzhou Medical University, Xuzhou, China, Laboratory of Infection and Immunity, Department of Pathogenic Biology and Immunology, School of Basic Medical Sciences, Xuzhou Medical University, Xuzhou, China

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• Longxiang Liao,

  Roles Investigation, Validation

  Affiliations Jiangsu Key Laboratory of Immunity and Metabolism, Xuzhou Medical University, Xuzhou, China, Laboratory of Infection and Immunity, Department of Pathogenic Biology and Immunology, School of Basic Medical Sciences, Xuzhou Medical University, Xuzhou, China

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• Xiuwen Zhu,

  Roles Investigation, Validation

  Affiliations Jiangsu Key Laboratory of Immunity and Metabolism, Xuzhou Medical University, Xuzhou, China, Laboratory of Infection and Immunity, Department of Pathogenic Biology and Immunology, School of Basic Medical Sciences, Xuzhou Medical University, Xuzhou, China

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• Zhen Shi,

  Roles Investigation, Validation

  Affiliations Jiangsu Key Laboratory of Immunity and Metabolism, Xuzhou Medical University, Xuzhou, China, Laboratory of Infection and Immunity, Department of Pathogenic Biology and Immunology, School of Basic Medical Sciences, Xuzhou Medical University, Xuzhou, China

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• Yanxia Wei,

  Roles Data curation, Validation

  Affiliations Jiangsu Key Laboratory of Immunity and Metabolism, Xuzhou Medical University, Xuzhou, China, Laboratory of Infection and Immunity, Department of Pathogenic Biology and Immunology, School of Basic Medical Sciences, Xuzhou Medical University, Xuzhou, China

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• Yanbo Kou,

  Roles Data curation, Validation

  Affiliations Jiangsu Key Laboratory of Immunity and Metabolism, Xuzhou Medical University, Xuzhou, China, Laboratory of Infection and Immunity, Department of Pathogenic Biology and Immunology, School of Basic Medical Sciences, Xuzhou Medical University, Xuzhou, China

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• Yugang Wang

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Project administration, Resources, Supervision, Validation, Visualization, Writing – review & editing

  * E-mail: wangyg@xzhmu.edu.cn (YW); Liouzhuanzhuan12@163.com (ZL)

  Affiliations Jiangsu Key Laboratory of Immunity and Metabolism, Xuzhou Medical University, Xuzhou, China, Laboratory of Infection and Immunity, Department of Pathogenic Biology and Immunology, School of Basic Medical Sciences, Xuzhou Medical University, Xuzhou, China

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