Divergent functions of late ESCRT components in Giardia lamblia: Insights from subcellular distributions and protein interactions

Nabanita Patra; Nabanita Saha; Trisha Ghosh; Babai Hazra; Shirsha Samanta; Pritha Mandal; Avishikta Chatterjee; Abhrajyoti Ghosh; Sandipan Ganguly; Srimonti Sarkar

doi:10.1371/journal.pntd.0013700

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Open Access

Peer-reviewed

Research Article

Divergent functions of late ESCRT components in Giardia lamblia: Insights from subcellular distributions and protein interactions

Nabanita Patra ,

Contributed equally to this work with: Nabanita Patra, Nabanita Saha

Roles Conceptualization, Data curation, Formal analysis, Methodology, Visualization, Writing – original draft

Affiliation Department of Biological Sciences, Bose Institute, Sector V, Bidhannagar, West Bengal, India
⨯
Nabanita Saha ,

Contributed equally to this work with: Nabanita Patra, Nabanita Saha

Roles Conceptualization, Data curation, Methodology

Current Address: Michigan Medicine, University of Michigan, Ann Arbor

Affiliation Department of Biological Sciences, Bose Institute, Sector V, Bidhannagar, West Bengal, India
⨯
Trisha Ghosh,

Roles Data curation, Formal analysis, Methodology

Affiliation Department of Biological Sciences, Bose Institute, Sector V, Bidhannagar, West Bengal, India
⨯
Babai Hazra,

Roles Data curation, Methodology

Affiliation Department of Biological Sciences, Bose Institute, Sector V, Bidhannagar, West Bengal, India
⨯
Shirsha Samanta,

Roles Data curation, Methodology

Affiliation Department of Biological Sciences, Bose Institute, Sector V, Bidhannagar, West Bengal, India
⨯
Pritha Mandal,

Roles Data curation, Methodology

Affiliation Department of Biological Sciences, Bose Institute, Sector V, Bidhannagar, West Bengal, India
⨯
Avishikta Chatterjee,

Roles Methodology

Affiliation Department of Biological Sciences, Bose Institute, Sector V, Bidhannagar, West Bengal, India
⨯
Abhrajyoti Ghosh,

Roles Methodology, Supervision

Affiliation Department of Biological Sciences, Bose Institute, Sector V, Bidhannagar, West Bengal, India
⨯
Sandipan Ganguly,

Roles Methodology, Resources

Affiliation Division of Parasitology, National Institute for Research in Bacterial Infections, Beliaghata, Kolkata, West Bengal, India
⨯
Srimonti Sarkar

Roles Conceptualization, Funding acquisition, Investigation, Project administration, Resources, Supervision, Validation, Visualization, Writing – review & editing

* E-mail: srimonti@jcbose.ac.in

Affiliation Department of Biological Sciences, Bose Institute, Sector V, Bidhannagar, West Bengal, India

https://orcid.org/0000-0002-5058-1208

⨯

Divergent functions of late ESCRT components in Giardia lamblia: Insights from subcellular distributions and protein interactions

Nabanita Patra,
Nabanita Saha,
Trisha Ghosh,
Babai Hazra,
Shirsha Samanta,
Pritha Mandal,
Avishikta Chatterjee,
Abhrajyoti Ghosh,
Sandipan Ganguly,
Srimonti Sarkar

Published: November 12, 2025
https://doi.org/10.1371/journal.pntd.0013700

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Trophozoites
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Cell membranes
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Giardia
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Yeast
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Flagella
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Protein domains
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Giardia lamblia
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