Age- and sex-associated differences in Lujo hemorrhagic fever pathogenesis in strain 13/N guinea pigs

Nikesh Tailor; Jérémie Prévost; Geoff Soule; Yvon Deschambault; Angela Sloan; Mable Chan; David Safronetz

doi:10.1371/journal.pntd.0013633

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Open Access

Peer-reviewed

Research Article

Age- and sex-associated differences in Lujo hemorrhagic fever pathogenesis in strain 13/N guinea pigs

Nikesh Tailor,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

Affiliation Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada
⨯
Jérémie Prévost,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

Affiliation Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada
⨯
Geoff Soule,

Roles Investigation, Writing – review & editing

Affiliation Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada
⨯
Yvon Deschambault,

Roles Investigation, Writing – review & editing

Affiliation Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada
⨯
Angela Sloan,

Roles Conceptualization, Methodology, Writing – review & editing

Affiliation Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada
⨯
Mable Chan,

Roles Investigation, Writing – review & editing

Affiliation Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada
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David Safronetz

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

* E-mail: david.safronetz@phac-aspc.gc.ca

Affiliations Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada, Department of Medical Microbiology and Infectious Diseases, Max Rady College of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada

https://orcid.org/0000-0002-9024-728X

⨯

Age- and sex-associated differences in Lujo hemorrhagic fever pathogenesis in strain 13/N guinea pigs

Nikesh Tailor,
Jérémie Prévost,
Geoff Soule,
Yvon Deschambault,
Angela Sloan,
Mable Chan,
David Safronetz

Published: October 21, 2025
https://doi.org/10.1371/journal.pntd.0013633

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