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Open Access
Peer-reviewed
Research Article
BFD2 mediates inflammation, apoptosis, and pre-anxiety-like behaviors induced by acute Toxoplasma gondii infection
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Xiaocheng Zhang,
Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Writing – original draft, Writing – review & editing
Affiliations National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, Beijing, China, Key Laboratory of Parasite and Vector Biology, National Health Commission of the People’s Republic of China, Shanghai, China, World Health Organization Collaborating Centre for Tropical Diseases, Shanghai, China, National Institute of Parasitic Diseases at Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), Shanghai, China, The School of Global Health, Chinese Center for Tropical Diseases Research, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Tanzhen Xu,
Roles Formal analysis, Methodology
Affiliation Department of Clinical Pharmacy, Fuyang Cancer Hospital, Fuyang, China
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Jinjin Zhu,
Roles Methodology
Affiliation Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Anhui Medical University, Hefei, China
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Hui Peng,
Roles Methodology
Affiliations National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, Beijing, China, Key Laboratory of Parasite and Vector Biology, National Health Commission of the People’s Republic of China, Shanghai, China, World Health Organization Collaborating Centre for Tropical Diseases, Shanghai, China, National Institute of Parasitic Diseases at Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), Shanghai, China
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Zixin Wei,
Roles Methodology
Affiliation Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China
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Lijun Cui,
Roles Methodology
Affiliations National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, Beijing, China, Key Laboratory of Parasite and Vector Biology, National Health Commission of the People’s Republic of China, Shanghai, China, World Health Organization Collaborating Centre for Tropical Diseases, Shanghai, China, National Institute of Parasitic Diseases at Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), Shanghai, China
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Qingqiu Zuo,
Roles Methodology
Affiliations National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, Beijing, China, Key Laboratory of Parasite and Vector Biology, National Health Commission of the People’s Republic of China, Shanghai, China, World Health Organization Collaborating Centre for Tropical Diseases, Shanghai, China, National Institute of Parasitic Diseases at Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), Shanghai, China
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Hua Liu,
Roles Methodology
Affiliations National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, Beijing, China, Key Laboratory of Parasite and Vector Biology, National Health Commission of the People’s Republic of China, Shanghai, China, World Health Organization Collaborating Centre for Tropical Diseases, Shanghai, China, National Institute of Parasitic Diseases at Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), Shanghai, China
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Yuan Hu,
Roles Formal analysis
Affiliations National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, Beijing, China, Key Laboratory of Parasite and Vector Biology, National Health Commission of the People’s Republic of China, Shanghai, China, World Health Organization Collaborating Centre for Tropical Diseases, Shanghai, China, National Institute of Parasitic Diseases at Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), Shanghai, China
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Jianping Cao
Roles Conceptualization, Formal analysis, Funding acquisition, Supervision, Writing – review & editing
* E-mail: caojp@chinacdc.cn
Affiliations National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, Beijing, China, Key Laboratory of Parasite and Vector Biology, National Health Commission of the People’s Republic of China, Shanghai, China, World Health Organization Collaborating Centre for Tropical Diseases, Shanghai, China, National Institute of Parasitic Diseases at Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), Shanghai, China, The School of Global Health, Chinese Center for Tropical Diseases Research, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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BFD2 mediates inflammation, apoptosis, and pre-anxiety-like behaviors induced by acute Toxoplasma gondii infection
- Xiaocheng Zhang,
- Tanzhen Xu,
- Jinjin Zhu,
- Hui Peng,
- Zixin Wei,
- Lijun Cui,
- Qingqiu Zuo,
- Hua Liu,
- Yuan Hu,
- Jianping Cao
- Published: September 4, 2025
- https://doi.org/10.1371/journal.pntd.0013428