Limited efficacy of cold and heat therapy as adjunctive treatments for local and functional outcomes of Bothrops atrox snakebite envenomation: A randomized clinical trial

• Mailma Costa de Almeida,

  Roles Data curation, Formal analysis, Investigation, Methodology, Resources, Supervision, Validation, Visualization, Writing – original draft

  Affiliations School of Health Sciences, Universidade do Estado do Amazonas, Manaus, Amazonas, Brazil, Department of Teaching and Research, Fundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, Amazonas, Brazil

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• Kathleen Maclenny Pereira Carvalho,

  Roles Data curation, Investigation, Visualization, Writing – original draft

  Affiliations School of Health Sciences, Universidade do Estado do Amazonas, Manaus, Amazonas, Brazil, Department of Teaching and Research, Fundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, Amazonas, Brazil

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• Yasmim da Silva Mendes,

  Roles Data curation, Investigation, Visualization, Writing – original draft

  Affiliations School of Health Sciences, Universidade do Estado do Amazonas, Manaus, Amazonas, Brazil, Department of Teaching and Research, Fundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, Amazonas, Brazil

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• Debora Nery Oliveira,

  Roles Data curation, Investigation, Visualization, Writing – original draft

  Affiliations School of Health Sciences, Universidade do Estado do Amazonas, Manaus, Amazonas, Brazil, Department of Teaching and Research, Fundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, Amazonas, Brazil

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• Érica da Silva Carvalho,

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft

  Affiliations School of Health Sciences, Universidade do Estado do Amazonas, Manaus, Amazonas, Brazil, Department of Teaching and Research, Fundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, Amazonas, Brazil

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• Marco Aurélio Sartim,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Teaching and Research, Fundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, Amazonas, Brazil, School of Pharmaceutical Science, Universidade Federal do Amazonas, Manaus, Amazonas, Brazil

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• Felipe Queiroz Araújo,

  Roles Data curation, Formal analysis, Investigation, Visualization, Writing – original draft

  Affiliations School of Health Sciences, Universidade do Estado do Amazonas, Manaus, Amazonas, Brazil, Department of Teaching and Research, Fundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, Amazonas, Brazil

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• André Sachett,

  Roles Data curation, Formal analysis, Methodology, Visualization, Writing – original draft

  Affiliation Department of Teaching and Research, Fundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, Amazonas, Brazil

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• João Ricardo Nickenig Vissoci,

  Roles Conceptualization, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Duke Department Emergency Medicine and Duke Global Health Institute (DGHI), Duke University, Durham, North Carolina, United States of America

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• Fernando Almeida-Val,

  Roles Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliations School of Health Sciences, Universidade do Estado do Amazonas, Manaus, Amazonas, Brazil, Department of Teaching and Research, Fundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, Amazonas, Brazil

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• Daniel Barros de Castro,

  Roles Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Teaching and Research, Fundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, Amazonas, Brazil

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• Wuelton Monteiro,

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations School of Health Sciences, Universidade do Estado do Amazonas, Manaus, Amazonas, Brazil, Department of Teaching and Research, Fundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, Amazonas, Brazil, School of Pharmaceutical Science, Universidade Federal do Amazonas, Manaus, Amazonas, Brazil, Duke Department Emergency Medicine and Duke Global Health Institute (DGHI), Duke University, Durham, North Carolina, United States of America

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• Jacqueline de Almeida Gonçalves Sachett

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: jac.sachett@gmail.com

  Affiliations School of Health Sciences, Universidade do Estado do Amazonas, Manaus, Amazonas, Brazil, Department of Teaching and Research, Fundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, Amazonas, Brazil

  https://orcid.org/0000-0001-5723-9977

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