Microbiota-derived indole differentially shapes Entamoeba histolytica physiology and promotes host-compatible colonization

• Eva Zanditenas ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  ¶‡ co-first authors.

  Affiliation Department of Molecular Microbiology, The Bruce and Ruth Rappaport Faculty of Medicine, Technion – Israel Institute of Technology, Haifa, Israel

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• Yumiko Saito-Nakano ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

  ¶‡ co-first authors.

  Affiliation Department of Parasitology, National Institute of Infectious Diseases, Japan Institute for Health Security, Japan

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• Meirav Trebicz Geffen,

  Roles Data curation, Investigation, Methodology, Project administration, Supervision, Writing – review & editing

  Affiliation Department of Molecular Microbiology, The Bruce and Ruth Rappaport Faculty of Medicine, Technion – Israel Institute of Technology, Haifa, Israel

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• Seiki Kobayashi,

  Roles Investigation, Methodology

  Affiliation Department of Parasitology, National Institute of Infectious Diseases, Japan Institute for Health Security, Japan

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• Hajime Hisaeda,

  Roles Investigation, Methodology

  Affiliation Department of Parasitology, National Institute of Infectious Diseases, Japan Institute for Health Security, Japan

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• Tomoyoshi Nozaki,

  Roles Investigation, Methodology, Supervision, Writing – review & editing

  Affiliation Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

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• Yuanning Guo,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Genetics and Developmental Biology, The Bruce and Ruth Rappaport Faculty of Medicine, Technion – Israel Institute of Technology, Haifa, Israel

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• Smruti Mahapatra,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Molecular Microbiology, The Bruce and Ruth Rappaport Faculty of Medicine, Technion – Israel Institute of Technology, Haifa, Israel

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• Haguy Wolfenson,

  Roles Methodology, Resources, Supervision, Writing – review & editing

  Affiliation Department of Genetics and Developmental Biology, The Bruce and Ruth Rappaport Faculty of Medicine, Technion – Israel Institute of Technology, Haifa, Israel

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• Serge Ankri

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: sankri@technion.ac.il

  Affiliation Department of Molecular Microbiology, The Bruce and Ruth Rappaport Faculty of Medicine, Technion – Israel Institute of Technology, Haifa, Israel

  https://orcid.org/0000-0002-8775-1557

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