Impact of inactivation methods on biosafety and antigen reactivity of Brucella melitensis from the perspective of Astral-DIA proteomics based on antibody immunoprecipitation mass spectrometry

• Yijian Liu ,

  Contributed equally to this work with: Yijian Liu, Jiazhen Ge

  Roles Investigation, Methodology, Writing – original draft

  Affiliation State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China

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• Jiazhen Ge ,

  Contributed equally to this work with: Yijian Liu, Jiazhen Ge

  Roles Conceptualization, Formal analysis, Methodology, Writing – original draft, Writing – review & editing

  Affiliations State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China, College of Veterinary Medicine, Gansu Agricultural University, Lanzhou, China

  https://orcid.org/0009-0004-0976-2607

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• Guodong Song,

  Roles Formal analysis, Validation

  Affiliation State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China

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• Pengcheng Gao,

  Roles Investigation, Resources

  Affiliation State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China

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• Mengzhu Qi,

  Roles Investigation

  Affiliation State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China

  ⨯
• Wenhao Wang,

  Roles Investigation

  Affiliations State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China, College of Animal Science and Technology, Shihezi University, Shihezi, China

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• Yingying Xie,

  Roles Investigation

  Affiliations State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China

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• Ziqing Wang,

  Roles Investigation

  Affiliations State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China, College of Animal Medicine, Xinjiang Agricultural University, Urumqi, China

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• Renge Li,

  Roles Resources

  Affiliations State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China, College of Veterinary Medicine, Gansu Agricultural University, Lanzhou, China

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• Yuefeng Chu ,

  Roles Funding acquisition, Project administration, Supervision

  * E-mail: zhengfuying@caas.cn (FZ); chuyuefeng@caas.cn (YC)

  Affiliations State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China, Gansu Province Research Center for Basic Disciplines of Pathogen Biology, Lanzhou, China, Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Ruminant Disease Prevention and Control (West), Ministry of Agricultural and Rural Affairs, Lanzhou, China

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• Fuying Zheng

  Roles Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: zhengfuying@caas.cn (FZ); chuyuefeng@caas.cn (YC)

  Affiliation State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China

  https://orcid.org/0009-0001-9151-583X

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