Intestinal inflammation induced by heat-labile toxin-producing enterotoxigenic E: Coli infection and impact on immune responses in an experimental human challenge model

• Xueyan Zhang ,

  Contributed equally to this work with: Xueyan Zhang, Jessica Brubaker

  Roles Formal analysis, Software, Visualization, Writing – original draft

  Affiliation Department of International Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, United States of America

  ⨯
• Jessica Brubaker ,

  Contributed equally to this work with: Xueyan Zhang, Jessica Brubaker

  Roles Data curation, Investigation, Methodology

  Affiliation Department of International Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, United States of America

  ⨯
• Kawsar R. Talaat,

  Roles Investigation, Project administration, Writing – review & editing

  Affiliation Department of International Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, United States of America

  ⨯
• Chad K. Porter,

  Roles Investigation, Writing – review & editing

  Affiliation Naval Medical Research Command, Silver Spring, Maryland, United States of America

  ⨯
• Brittany L. Feijoo,

  Roles Investigation, Writing – review & editing

  Affiliation Department of International Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, United States of America

  ⨯
• Brittany M. Adjoodani,

  Roles Investigation, Writing – review & editing

  Affiliation Department of International Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, United States of America

  ⨯
• Barbara DeNearing,

  Roles Investigation, Writing – review & editing

  Affiliation Department of International Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, United States of America

  ⨯
• Michael G. Prouty,

  Roles Writing – review & editing

  Affiliation Naval Medical Research Command, Silver Spring, Maryland, United States of America

  ⨯
• A Louis Bourgeois,

  Roles Writing – review & editing

  Affiliation Department of International Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, United States of America

  ⨯
• David A. Sack,

  Roles Writing – review & editing

  Affiliation Department of International Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, United States of America

  ⨯
• Susanne Eder-Lingelbach,

  Roles Resources, Writing – review & editing

  Affiliation Valneva, Austria GmbH, Vienna, Austria

  ⨯
• Christian Taucher,

  Roles Resources, Writing – review & editing

  Affiliation Valneva, Austria GmbH, Vienna, Austria

  ⨯
• Subhra Chakraborty

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – review & editing

  * E-mail: schakr11@jhu.edu

  Affiliation Department of International Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, United States of America

  https://orcid.org/0000-0002-6446-0255

  ⨯