Development of a novel multi-epitope mRNA vaccine candidate to combat SFTSV pandemic

• Fei Zhu ,

  Contributed equally to this work with: Fei Zhu, Shiyang Ma

  Roles Conceptualization, Methodology, Software

  Affiliations Department of Respiratory Medicine, National Key Clinical Specialty, Branch of National Clinical Research Center for Respiratory Disease, Xiangya Hospital, Central South University, Changsha, China, Center of Respiratory Medicine, Xiangya Hospital, Central South University, Changsha, China, Clinical Research Center for Respiratory Diseases in Hunan Province, Changsha, China, Hunan Engineering Research Center for Intelligent Diagnosis and Treatment of Respiratory Disease, Changsha, China, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Changsha, China

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• Shiyang Ma ,

  Contributed equally to this work with: Fei Zhu, Shiyang Ma

  Roles Conceptualization, Methodology, Software, Validation, Writing – original draft

  Affiliations Department of Respiratory Medicine, National Key Clinical Specialty, Branch of National Clinical Research Center for Respiratory Disease, Xiangya Hospital, Central South University, Changsha, China, Center of Respiratory Medicine, Xiangya Hospital, Central South University, Changsha, China, Clinical Research Center for Respiratory Diseases in Hunan Province, Changsha, China, Hunan Engineering Research Center for Intelligent Diagnosis and Treatment of Respiratory Disease, Changsha, China, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Changsha, China

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• Yizhong Xu,

  Roles Formal analysis, Validation

  Affiliations Department of Respiratory Medicine, National Key Clinical Specialty, Branch of National Clinical Research Center for Respiratory Disease, Xiangya Hospital, Central South University, Changsha, China, Center of Respiratory Medicine, Xiangya Hospital, Central South University, Changsha, China, Clinical Research Center for Respiratory Diseases in Hunan Province, Changsha, China, Hunan Engineering Research Center for Intelligent Diagnosis and Treatment of Respiratory Disease, Changsha, China, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Changsha, China

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• Ziyou Zhou,

  Roles Formal analysis, Validation, Writing – original draft

  Affiliations Department of Respiratory Medicine, National Key Clinical Specialty, Branch of National Clinical Research Center for Respiratory Disease, Xiangya Hospital, Central South University, Changsha, China, Center of Respiratory Medicine, Xiangya Hospital, Central South University, Changsha, China, Clinical Research Center for Respiratory Diseases in Hunan Province, Changsha, China, Hunan Engineering Research Center for Intelligent Diagnosis and Treatment of Respiratory Disease, Changsha, China, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Changsha, China

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• Peipei Zhang,

  Roles Software, Writing – original draft

  Affiliations Department of Respiratory Medicine, National Key Clinical Specialty, Branch of National Clinical Research Center for Respiratory Disease, Xiangya Hospital, Central South University, Changsha, China, Center of Respiratory Medicine, Xiangya Hospital, Central South University, Changsha, China, Clinical Research Center for Respiratory Diseases in Hunan Province, Changsha, China, Hunan Engineering Research Center for Intelligent Diagnosis and Treatment of Respiratory Disease, Changsha, China, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Changsha, China

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• Wenzhong Peng,

  Roles Validation

  Affiliations Department of Respiratory Medicine, National Key Clinical Specialty, Branch of National Clinical Research Center for Respiratory Disease, Xiangya Hospital, Central South University, Changsha, China, Center of Respiratory Medicine, Xiangya Hospital, Central South University, Changsha, China, Clinical Research Center for Respiratory Diseases in Hunan Province, Changsha, China, Hunan Engineering Research Center for Intelligent Diagnosis and Treatment of Respiratory Disease, Changsha, China, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Changsha, China

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• Hang Yang,

  Roles Methodology, Software

  Affiliations Department of Respiratory Medicine, National Key Clinical Specialty, Branch of National Clinical Research Center for Respiratory Disease, Xiangya Hospital, Central South University, Changsha, China, Center of Respiratory Medicine, Xiangya Hospital, Central South University, Changsha, China, Clinical Research Center for Respiratory Diseases in Hunan Province, Changsha, China, Hunan Engineering Research Center for Intelligent Diagnosis and Treatment of Respiratory Disease, Changsha, China, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Changsha, China

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• Caixia Tan,

  Roles Software, Writing – original draft

  Affiliation Department of Infection Control Center, Xiangya Hospital, Central South University, Changsha, China

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• Jie Chen ,

  Roles Conceptualization, Methodology, Visualization, Writing – review & editing

  * E-mail: pinhuapan668@csu.edu.cn (PP); chenjie869@csu.edu.cn (JC)

  Affiliations Department of Respiratory Medicine, National Key Clinical Specialty, Branch of National Clinical Research Center for Respiratory Disease, Xiangya Hospital, Central South University, Changsha, China, Center of Respiratory Medicine, Xiangya Hospital, Central South University, Changsha, China, Clinical Research Center for Respiratory Diseases in Hunan Province, Changsha, China, Hunan Engineering Research Center for Intelligent Diagnosis and Treatment of Respiratory Disease, Changsha, China, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Changsha, China

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• Pinhua Pan

  Roles Funding acquisition, Project administration, Supervision

  * E-mail: pinhuapan668@csu.edu.cn (PP); chenjie869@csu.edu.cn (JC)

  Affiliations Department of Respiratory Medicine, National Key Clinical Specialty, Branch of National Clinical Research Center for Respiratory Disease, Xiangya Hospital, Central South University, Changsha, China, Center of Respiratory Medicine, Xiangya Hospital, Central South University, Changsha, China, Clinical Research Center for Respiratory Diseases in Hunan Province, Changsha, China, Hunan Engineering Research Center for Intelligent Diagnosis and Treatment of Respiratory Disease, Changsha, China, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Changsha, China

  https://orcid.org/00010000-0001-5883-0531

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