Randomized, observer-blind, controlled Phase 1 study of the safety and immunogenicity of the Na-GST-1/Alhydrogel hookworm vaccine with or without a CpG ODN adjuvant in hookworm-naïve adults

• David J. Diemert ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Visualization, Writing – original draft

  * E-mail: ddiemert@gwu.edu

  Affiliations Department of Medicine, School of Medicine and Health Sciences, The George Washington University, Washington, DC, United States of America, Department of Microbiology, Immunology and Tropical Medicine, School of Medicine and Health Sciences, The George Washington University, Washington, DC, United States of America

  https://orcid.org/0000-0002-2789-0512

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• Maria Zumer,

  Roles Data curation, Investigation, Project administration, Writing – review & editing

  Affiliation Department of Medicine, School of Medicine and Health Sciences, The George Washington University, Washington, DC, United States of America

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• Mark Bova,

  Roles Formal analysis, Visualization, Writing – original draft

  Affiliation Department of Epidemiology, Milken Institute School of Public Health, The George Washington University, Washington, DC, United States of America

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• Christina Gibbs-Tewary,

  Roles Data curation, Visualization, Writing – original draft

  Affiliation Department of Medicine, School of Medicine and Health Sciences, The George Washington University, Washington, DC, United States of America

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• Elissa M. Malkin,

  Roles Data curation, Formal analysis, Project administration, Writing – review & editing

  Affiliation Department of Medicine, School of Medicine and Health Sciences, The George Washington University, Washington, DC, United States of America

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• Doreen Campbell,

  Roles Conceptualization, Data curation, Project administration, Writing – review & editing

  Affiliation Department of Medicine, School of Medicine and Health Sciences, The George Washington University, Washington, DC, United States of America

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• Lara Hoeweler,

  Roles Data curation, Investigation, Visualization

  Affiliation Department of Microbiology, Immunology and Tropical Medicine, School of Medicine and Health Sciences, The George Washington University, Washington, DC, United States of America

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• Guangzhao Li,

  Roles Data curation, Formal analysis, Investigation, Visualization, Writing – review & editing

  Affiliation Department of Microbiology, Immunology and Tropical Medicine, School of Medicine and Health Sciences, The George Washington University, Washington, DC, United States of America

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• Maria Elena Bottazzi,

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing

  Affiliations Division of Pediatric Tropical Medicine, Department of Pediatrics, National School of Tropical Medicine, Texas Children’s Hospital Center for Vaccine Development, Baylor College of Medicine, Houston, Texas, United States of America, Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, United States of America

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• Peter J. Hotez,

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing

  Affiliations Division of Pediatric Tropical Medicine, Department of Pediatrics, National School of Tropical Medicine, Texas Children’s Hospital Center for Vaccine Development, Baylor College of Medicine, Houston, Texas, United States of America, Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, United States of America

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• Jeffrey M. Bethony

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – original draft

  Affiliation Department of Microbiology, Immunology and Tropical Medicine, School of Medicine and Health Sciences, The George Washington University, Washington, DC, United States of America

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