Pharmacological inhibition of key metabolic pathways attenuates Leishmania spp infection in macrophages

• Elaine Carvalho de Oliveira ,

  Roles Data curation, Formal analysis, Methodology, Validation, Writing – original draft

  ¶‡ Contributed equally to this study (co-first authors).

  Affiliation Instituto Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, Brazil

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• Rafael Tibúrcio ,

  Roles Conceptualization, Formal analysis, Writing – original draft, Writing – review & editing

  ¶‡ Contributed equally to this study (co-first authors).

  Affiliation University of California San Francisco, Department of Medicine, San Francisco, California, United States

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• Gabriela Duarte,

  Roles Investigation, Methodology, Validation

  Affiliation Instituto Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, Brazil

  ⨯
• Amanda Lago,

  Roles Investigation, Methodology, Validation

  Affiliation Instituto Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, Brazil

  ⨯
• Léon de Melo,

  Roles Methodology

  Affiliation University of Calgary, Departments of Microbiology, Immunology and Infectious Diseases, Calgary, Alberta, Canada

  ⨯
• Sara Nunes,

  Roles Data curation, Visualization

  Affiliation Instituto Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, Brazil

  ⨯
• Gustavo Gastão Davanzo,

  Roles Conceptualization, Data curation, Investigation, Methodology, Validation

  Affiliation University of Campinas, Department of Genetics, Evolution, Microbiology and Immunology, São Paulo, Brazil

  ⨯
• Ana Júlia Martins,

  Roles Methodology

  Affiliation University of Campinas, Department of Genetics, Evolution, Microbiology and Immunology, São Paulo, Brazil

  ⨯
• Bruno Vinagre Ribeiro,

  Roles Software

  Affiliation Instituto Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, Brazil

  ⨯
• Deborah Mothé,

  Roles Investigation

  Affiliation Instituto Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, Brazil

  ⨯
• Juliana B. P. Menezes,

  Roles Conceptualization, Formal analysis, Writing – review & editing

  Affiliation Instituto Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, Brazil

  ⨯
• Patrícia Veras,

  Roles Methodology, Supervision, Validation

  Affiliation Instituto Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, Brazil

  ⨯
• Natalia Tavares,

  Roles Conceptualization, Investigation, Writing – review & editing

  Affiliation Instituto Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, Brazil

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• Pedro M. Moraes-Vieira,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Writing – review & editing

  Affiliation University of Campinas, Department of Genetics, Evolution, Microbiology and Immunology, São Paulo, Brazil

  ⨯
• Cláudia Ida Brodskyn

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Writing – review & editing

  * E-mail: claudia.brodskyn@fiocruz.br, cbrodskyn2009@gmail.com

  Affiliation Instituto Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, Brazil

  https://orcid.org/0000-0003-3367-5365

  ⨯