An experimental target-based platform in yeast for screening Plasmodium vivax deoxyhypusine synthase inhibitors

• Suélen Fernandes Silva,

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Chemistry and Molecular Biology, University of Gothenburg, Göteborg, Sweden, Chemistry Institute, São Paulo State University - UNESP, Araraquara, São Paulo, Brazil, Center for Medicinal Chemistry - CQMED, Center for Molecular Biology and Genetic Engineering - CBMEG, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil

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• Angélica Hollunder Klippel,

  Roles Conceptualization, Investigation, Methodology, Writing – review & editing

  Affiliations Center for Medicinal Chemistry - CQMED, Center for Molecular Biology and Genetic Engineering - CBMEG, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil, School of Pharmaceutical Sciences, São Paulo State University—UNESP, Araraquara, São Paulo, Brazil

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• Sunniva Sigurdardóttir,

  Roles Conceptualization, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Chemistry and Molecular Biology, University of Gothenburg, Göteborg, Sweden

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• Sayyed Jalil Mahdizadeh,

  Roles Software, Supervision, Writing – review & editing

  Affiliation Department of Chemistry and Molecular Biology, University of Gothenburg, Göteborg, Sweden

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• Ievgeniia Tiukova,

  Roles Methodology, Resources, Writing – review & editing

  Affiliation Department of Life Sciences, Chalmers, Göteborg, Sweden

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• Catarina Bourgard,

  Roles Investigation, Writing – review & editing

  Affiliations Department of Chemistry and Molecular Biology, University of Gothenburg, Göteborg, Sweden, Laboratory of Tropical Diseases, Institute of Biology, Universidade Estadual de Campinas - UNICAMP, Campinas, São Paulo, Brazil

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• Luis Carlos Salazar-Alvarez,

  Roles Investigation, Visualization, Writing – review & editing

  Affiliation Laboratory of Tropical Diseases, Institute of Biology, Universidade Estadual de Campinas - UNICAMP, Campinas, São Paulo, Brazil

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• Heloísa Monteiro do Amaral Prado,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Center for Medicinal Chemistry - CQMED, Center for Molecular Biology and Genetic Engineering - CBMEG, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil

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• Renan Vinicius de Araujo,

  Roles Investigation, Writing – review & editing

  Affiliation Center for Medicinal Chemistry - CQMED, Center for Molecular Biology and Genetic Engineering - CBMEG, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil

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• Fabio Trindade Maranhão Costa,

  Roles Funding acquisition, Supervision, Writing – review & editing

  Affiliation Laboratory of Tropical Diseases, Institute of Biology, Universidade Estadual de Campinas - UNICAMP, Campinas, São Paulo, Brazil

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• Elizabeth Bilsland,

  Roles Supervision, Writing – review & editing

  Affiliation Department of Structural and Functional Biology, Institute of Biology, Universidade Estadual de Campinas - UNICAMP, Campinas, São Paulo, Brazil

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• Ross D. King,

  Roles Methodology, Resources, Writing – review & editing

  Affiliation Department of Life Sciences, Chalmers, Göteborg, Sweden

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• Katlin Brauer Massirer,

  Roles Funding acquisition, Methodology, Resources, Supervision, Writing – review & editing

  Affiliation Center for Medicinal Chemistry - CQMED, Center for Molecular Biology and Genetic Engineering - CBMEG, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil

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• Leif A. Eriksson,

  Roles Funding acquisition, Methodology, Resources, Software, Supervision, Writing – review & editing

  Affiliation Department of Chemistry and Molecular Biology, University of Gothenburg, Göteborg, Sweden

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• Mário Henrique Bengtson,

  Roles Methodology, Resources, Supervision, Writing – review & editing

  Affiliations Center for Medicinal Chemistry - CQMED, Center for Molecular Biology and Genetic Engineering - CBMEG, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil, Department of Biochemistry and Tissue Biology, Institute of Biology, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil

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• Cleslei Fernando Zanelli,

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – review & editing

  Affiliations Chemistry Institute, São Paulo State University - UNESP, Araraquara, São Paulo, Brazil, School of Pharmaceutical Sciences, São Paulo State University—UNESP, Araraquara, São Paulo, Brazil

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•  [ ... ],
• Per Sunnerhagen

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: per.sunnerhagen@cmb.gu.se

  Affiliation Department of Chemistry and Molecular Biology, University of Gothenburg, Göteborg, Sweden

  https://orcid.org/0000-0002-0967-8729

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