A single dose recombinant AAV based CHIKV vaccine elicits robust and durable protective antibody responses in mice

• Qin-Xuan Zhu ,

  Contributed equally to this work with: Qin-Xuan Zhu, Ya-Nan Zhang

  Roles Data curation, Investigation, Methodology

  Affiliation School of Medical Technology and Translational Medicine, Hunan Normal University, Changsha, China

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• Ya-Nan Zhang ,

  Contributed equally to this work with: Qin-Xuan Zhu, Ya-Nan Zhang

  Roles Data curation, Formal analysis, Methodology

  Affiliation Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, China

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• Hong-Qing Zhang,

  Roles Data curation, Formal analysis, Methodology

  Affiliations Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, China, University of Chinese Academy of Sciences, Beijing China

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• Chao Leng,

  Roles Resources

  Affiliation Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, China

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• Cheng-Lin Deng,

  Roles Formal analysis, Methodology

  Affiliation Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, China

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• Xin Wang,

  Roles Investigation, Methodology

  Affiliation School of Medical Technology and Translational Medicine, Hunan Normal University, Changsha, China

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• Jia-Jia Li,

  Roles Data curation, Investigation

  Affiliation School of Medical Technology and Translational Medicine, Hunan Normal University, Changsha, China

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• Xiang-Li Ye,

  Roles Writing – review & editing

  Affiliation School of Medical Technology and Translational Medicine, Hunan Normal University, Changsha, China

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• Bo Zhang ,

  Roles Conceptualization, Formal analysis, Funding acquisition, Supervision, Validation

  * E-mail: lxd@live.cn (XDL); zhangbo@wh.iov.cn (BZ)

  Affiliation Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, China

  https://orcid.org/0000-0002-8895-3679

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• Xiao-Dan Li

  Roles Conceptualization, Data curation, Investigation, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: lxd@live.cn (XDL); zhangbo@wh.iov.cn (BZ)

  Affiliation School of Medical Technology and Translational Medicine, Hunan Normal University, Changsha, China

  https://orcid.org/0000-0002-4953-6709

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