Ghrelin is involved in regulating the progression of Echinococcus Granulosus-infected liver lesions through suppression of immunoinflammation and fibrosis

Jiang Zhu; Hongqiong Zhao; Aili Aierken; Tanfang Zhou; Meng Menggen; Huijing Gao; Rongdong He; Kalibixiati Aimulajiang; Hao Wen

doi:10.1371/journal.pntd.0012587

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Open Access

Peer-reviewed

Research Article

Ghrelin is involved in regulating the progression of Echinococcus Granulosus-infected liver lesions through suppression of immunoinflammation and fibrosis

Jiang Zhu,

Roles Methodology, Software, Visualization, Writing – original draft

Affiliations State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Clinical Medicine Institute, The First Affiliated Hospital of Xinjiang Medical University, Xinjiang, China, Department of Hepatobiliary and Hydatid Disease, Digestive and Vascular Surgery Center Therapy Center, The First Affiliated Hospital of Xinjiang Medical University, Xinjiang, China
⨯
Hongqiong Zhao,

Roles Conceptualization, Data curation, Formal analysis

Affiliation College of Veterinary Medicine, Xinjiang Agricultural University, Xinjiang, China
⨯
Aili Aierken,

Roles Investigation, Methodology, Software

Affiliation State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Clinical Medicine Institute, The First Affiliated Hospital of Xinjiang Medical University, Xinjiang, China
⨯
Tanfang Zhou,

Roles Conceptualization, Methodology

Affiliations State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Clinical Medicine Institute, The First Affiliated Hospital of Xinjiang Medical University, Xinjiang, China, Department of Hepatobiliary and Hydatid Disease, Digestive and Vascular Surgery Center Therapy Center, The First Affiliated Hospital of Xinjiang Medical University, Xinjiang, China
⨯
Meng Menggen,

Roles Formal analysis

Affiliation State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Clinical Medicine Institute, The First Affiliated Hospital of Xinjiang Medical University, Xinjiang, China
⨯
Huijing Gao,

Roles Resources, Visualization

Affiliation State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Clinical Medicine Institute, The First Affiliated Hospital of Xinjiang Medical University, Xinjiang, China
⨯
Rongdong He,

Roles Data curation, Methodology

Affiliations State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Clinical Medicine Institute, The First Affiliated Hospital of Xinjiang Medical University, Xinjiang, China, Department of Hepatobiliary and Hydatid Disease, Digestive and Vascular Surgery Center Therapy Center, The First Affiliated Hospital of Xinjiang Medical University, Xinjiang, China
⨯
Kalibixiati Aimulajiang ,

Roles Conceptualization, Data curation, Supervision, Visualization, Writing – original draft, Writing – review & editing

* E-mail: kali0920@163.com (KA); dr.wenhao@163.com (HW)

Affiliation State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Clinical Medicine Institute, The First Affiliated Hospital of Xinjiang Medical University, Xinjiang, China

https://orcid.org/0000-0003-4491-0359

⨯
Hao Wen

Roles Funding acquisition, Project administration, Supervision, Validation, Visualization, Writing – review & editing

* E-mail: kali0920@163.com (KA); dr.wenhao@163.com (HW)

Affiliations State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Clinical Medicine Institute, The First Affiliated Hospital of Xinjiang Medical University, Xinjiang, China, Department of Hepatobiliary and Hydatid Disease, Digestive and Vascular Surgery Center Therapy Center, The First Affiliated Hospital of Xinjiang Medical University, Xinjiang, China
⨯

Ghrelin is involved in regulating the progression of Echinococcus Granulosus-infected liver lesions through suppression of immunoinflammation and fibrosis

Jiang Zhu,
Hongqiong Zhao,
Aili Aierken,
Tanfang Zhou,
Meng Menggen,
Huijing Gao,
Rongdong He,
Kalibixiati Aimulajiang,
Hao Wen

Published: October 22, 2024
https://doi.org/10.1371/journal.pntd.0012587

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Ghrelin
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Protein expression
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Echinococcosis
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Cell-mediated immunity
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