Auranofin is active against Histoplasma capsulatum and reduces the expression of virulence-related genes

• Marcos de Abreu Almeida,

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft

  Affiliations Laboratório de Micologia, Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil, Departamento de Microbiologia e Parasitologia, Instituto Biomédico, Universidade Federal Fluminense, Niterói, Brazil

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• Lilian Cristiane Baeza,

  Roles Formal analysis, Investigation, Methodology, Validation, Writing – review & editing

  Affiliation Centro de Ciências Médicas e Farmacêuticas, Universidade Estadual do Oeste do Paraná, Cascavel, Brazil

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• Leandro B. R. Silva,

  Roles Formal analysis, Investigation, Methodology, Validation, Writing – review & editing

  Affiliations Departamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil, Department of Microbiology and Immunology, The University of British Columbia, Vancouver, Canada

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• Andréa Reis Bernardes-Engemann,

  Roles Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Laboratório de Micologia, Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil

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• Fernando Almeida-Silva,

  Roles Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Laboratório de Micologia, Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil

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• Rowena Alves Coelho,

  Roles Investigation, Methodology, Validation, Writing – review & editing

  Affiliation Laboratório de Micologia, Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil

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• Iara Bastos de Andrade,

  Roles Investigation, Methodology, Validation, Writing – review & editing

  Affiliation Laboratório de Biofísica de Fungos, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil

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• Dario Corrêa-Junior,

  Roles Formal analysis, Methodology, Visualization, Writing – review & editing

  Affiliation Laboratório de Biofísica de Fungos, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil

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• Susana Frases,

  Roles Methodology, Resources, Supervision, Validation, Writing – review & editing

  Affiliations Laboratório de Biofísica de Fungos, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil, Rede Micologia, FAPERJ, Rio de Janeiro, Brazil

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• Rosely Maria Zancopé-Oliveira,

  Roles Funding acquisition, Resources, Supervision, Writing – review & editing

  Affiliation Laboratório de Micologia, Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil

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• Alexandre Alanio,

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing

  Affiliation Institut Pasteur, Université Paris Cité, Centre National de Référence Mycoses Invasives et Antifongiques, Groupe de recherche Mycologie Translationnelle, Département de Mycologie, Paris, France

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• Carlos Pelleschi Taborda,

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing

  Affiliation Departamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil

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• Rodrigo Almeida-Paes

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Project administration, Resources, Supervision, Writing – original draft

  * E-mail: rodrigo.paes@ini.fiocruz.br

  Affiliations Laboratório de Micologia, Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil, Rede Micologia, FAPERJ, Rio de Janeiro, Brazil

  https://orcid.org/0000-0002-6639-6058

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