Circulating extracellular vesicles in sera of chronic patients as a method for determining active parasitism in Chagas disease

• Noelia Lozano ,

  Contributed equally to this work with: Noelia Lozano, Alexa Prescilla-Ledezma

  Roles Investigation, Methodology, Writing – original draft

  Affiliations Area of Parasitology, Department of Pharmacy and Pharmaceutical Technology and Parasitology, University of Valencia, Burjassot, Valencia, Spain, Department of Clinical Microbiology and Parasitology, Hospital Universitario y Politécnico La Fe, Martorell, Valencia, Spain

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• Alexa Prescilla-Ledezma ,

  Contributed equally to this work with: Noelia Lozano, Alexa Prescilla-Ledezma

  Roles Investigation, Methodology, Writing – original draft

  Affiliations Department of Human Microbiology, Faculty of Medicine, University of Panama, Panama, Department of Parasitology, Biochemical and Molecular Parasitology Group CTS-183, and Institute of Biotechnology, University of Granada., Granada, Spain

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• Eva Calabuig,

  Roles Investigation, Methodology, Validation, Writing – review & editing

  Affiliations Infectious Diseases Unit, Internal Medicine Department, Hospital Universitario y Politécnico La Fe, Martorell, Valencia, Spain, University of Valencia-Health Research Institute La Fe-IIS, Valencia, Spain

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• Maria Trelis,

  Roles Supervision, Validation, Writing – review & editing

  Affiliations Area of Parasitology, Department of Pharmacy and Pharmaceutical Technology and Parasitology, University of Valencia, Burjassot, Valencia, Spain, Joint Research Unit on Endocrinology, Nutrition and Clinical Dietetics, University of Valencia-Health Research Institute La Fe-IIS, Valencia, Spain

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• José Miguel Sahuquillo Arce,

  Roles Investigation, Methodology

  Affiliation Department of Clinical Microbiology and Parasitology, Hospital Universitario y Politécnico La Fe, Martorell, Valencia, Spain

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• José Luis López Hontangas,

  Roles Investigation, Methodology, Validation, Writing – original draft

  Affiliation Department of Clinical Microbiology and Parasitology, Hospital Universitario y Politécnico La Fe, Martorell, Valencia, Spain

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• Luis Miguel de Pablos,

  Roles Funding acquisition, Investigation, Validation, Writing – original draft, Writing – review & editing

  Affiliation Department of Parasitology, Biochemical and Molecular Parasitology Group CTS-183, and Institute of Biotechnology, University of Granada., Granada, Spain

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• Mercedes Gomez-Samblas ,

  Roles Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliation Department of Parasitology, Biochemical and Molecular Parasitology Group CTS-183, and Institute of Biotechnology, University of Granada., Granada, Spain

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• Antonio Osuna

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: aosuna@ugr.es

  ¶‡ These authors also contributed equally to this work.

  Affiliation Department of Parasitology, Biochemical and Molecular Parasitology Group CTS-183, and Institute of Biotechnology, University of Granada., Granada, Spain

  https://orcid.org/0000-0002-3818-1471

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