Potential selection of antimony and methotrexate cross-resistance in Leishmania infantum circulating strains

Lorena Bernardo; Ana Victoria Ibarra-Meneses; Noelie Douanne; Audrey Corbeil; Jose Carlos Solana; Francis Beaudry; Eugenia Carrillo; Javier Moreno; Christopher Fernandez-Prada

doi:10.1371/journal.pntd.0012015

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Peer-reviewed

Research Article

Potential selection of antimony and methotrexate cross-resistance in Leishmania infantum circulating strains

Lorena Bernardo,

Roles Formal analysis, Investigation, Validation, Writing – original draft

Affiliations WHO Collaborating Centre for Leishmaniasis, Spanish National Center for Microbiology, Instituto de Salud Carlos III (ISCIII), Majadahonda, Madrid, Spain, Centro de Investigación Biomédica en Red de Enfermedades Infecciosas (CIBERINFEC), ISCIII, Madrid, Spain
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Ana Victoria Ibarra-Meneses,

Roles Formal analysis, Investigation, Validation, Visualization, Writing – original draft

Affiliations Département de Pathologie et Microbiologie, Faculté de Médecine Vétérinaire, Université de Montréal, Saint-Hyacinthe, Quebec, Canada, The Research Group on Infectious Diseases in Production Animals (GREMIP), Faculté de Médecine Vétérinaire, Université de Montréal, Saint-Hyacinthe, Quebec, Canada
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Noelie Douanne,

Roles Investigation

Affiliations Département de Pathologie et Microbiologie, Faculté de Médecine Vétérinaire, Université de Montréal, Saint-Hyacinthe, Quebec, Canada, The Research Group on Infectious Diseases in Production Animals (GREMIP), Faculté de Médecine Vétérinaire, Université de Montréal, Saint-Hyacinthe, Quebec, Canada
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Audrey Corbeil,

Roles Investigation

Affiliations Département de Pathologie et Microbiologie, Faculté de Médecine Vétérinaire, Université de Montréal, Saint-Hyacinthe, Quebec, Canada, The Research Group on Infectious Diseases in Production Animals (GREMIP), Faculté de Médecine Vétérinaire, Université de Montréal, Saint-Hyacinthe, Quebec, Canada
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Jose Carlos Solana,

Roles Formal analysis

Affiliations WHO Collaborating Centre for Leishmaniasis, Spanish National Center for Microbiology, Instituto de Salud Carlos III (ISCIII), Majadahonda, Madrid, Spain, Centro de Investigación Biomédica en Red de Enfermedades Infecciosas (CIBERINFEC), ISCIII, Madrid, Spain
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Francis Beaudry,

Roles Formal analysis, Funding acquisition, Methodology, Validation, Visualization

Affiliations Département de Biomédecine, Faculté de Médecine Vétérinaire, Université de Montréal, Saint-Hyacinthe, Quebec, Canada, Centre de recherche sur le cerveau et l’apprentissage (CIRCA), Université de Montréal, Montréal, Quebec, Canada
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Eugenia Carrillo ,

Contributed equally to this work with: Eugenia Carrillo, Javier Moreno, Christopher Fernandez-Prada

Roles Formal analysis, Funding acquisition, Methodology, Resources, Supervision, Writing – original draft

Affiliations WHO Collaborating Centre for Leishmaniasis, Spanish National Center for Microbiology, Instituto de Salud Carlos III (ISCIII), Majadahonda, Madrid, Spain, Centro de Investigación Biomédica en Red de Enfermedades Infecciosas (CIBERINFEC), ISCIII, Madrid, Spain
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Javier Moreno ,

Contributed equally to this work with: Eugenia Carrillo, Javier Moreno, Christopher Fernandez-Prada

Roles Conceptualization, Formal analysis, Funding acquisition, Resources, Supervision, Validation, Writing – original draft

Affiliations WHO Collaborating Centre for Leishmaniasis, Spanish National Center for Microbiology, Instituto de Salud Carlos III (ISCIII), Majadahonda, Madrid, Spain, Centro de Investigación Biomédica en Red de Enfermedades Infecciosas (CIBERINFEC), ISCIII, Madrid, Spain
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Christopher Fernandez-Prada

Contributed equally to this work with: Eugenia Carrillo, Javier Moreno, Christopher Fernandez-Prada

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

* E-mail: christopher.fernandez.prada@umontreal.ca

Affiliations Département de Pathologie et Microbiologie, Faculté de Médecine Vétérinaire, Université de Montréal, Saint-Hyacinthe, Quebec, Canada, The Research Group on Infectious Diseases in Production Animals (GREMIP), Faculté de Médecine Vétérinaire, Université de Montréal, Saint-Hyacinthe, Quebec, Canada

https://orcid.org/0000-0003-4834-4956

⨯

Potential selection of antimony and methotrexate cross-resistance in Leishmania infantum circulating strains

Lorena Bernardo,
Ana Victoria Ibarra-Meneses,
Noelie Douanne,
Audrey Corbeil,
Jose Carlos Solana,
Francis Beaudry,
Eugenia Carrillo,
Javier Moreno,
Christopher Fernandez-Prada

Published: February 29, 2024
https://doi.org/10.1371/journal.pntd.0012015

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