The Rift Valley fever (RVF) vaccine candidate 40Fp8 shows an extreme attenuation in IFNARKO mice following intranasal inoculation

Belén Borrego; Celia Alonso; Sandra Moreno; Nuria de la Losa; Pedro José Sánchez-Cordón; Alejandro Brun

doi:10.1371/journal.pntd.0012011

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Peer-reviewed

Research Article

The Rift Valley fever (RVF) vaccine candidate 40Fp8 shows an extreme attenuation in IFNARKO mice following intranasal inoculation

Belén Borrego ,

Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: borrego@inia.csic.es (BB); brun@inia.csic.es (AB)

Affiliation Department of IMMUNOLOGY, PATHOLOGY AND CONTROL OF INFECTIOUS DISEASES, Centro de Investigación en Sanidad Animal CISA INIA/CSIC, Valdeolmos, Madrid, Spain

https://orcid.org/0000-0002-0801-9166

⨯
Celia Alonso,

Roles Formal analysis, Investigation, Methodology, Validation, Writing – original draft

Affiliation Department of IMMUNOLOGY, PATHOLOGY AND CONTROL OF INFECTIOUS DISEASES, Centro de Investigación en Sanidad Animal CISA INIA/CSIC, Valdeolmos, Madrid, Spain
⨯
Sandra Moreno,

Roles Investigation, Methodology, Resources

Affiliation Department of IMMUNOLOGY, PATHOLOGY AND CONTROL OF INFECTIOUS DISEASES, Centro de Investigación en Sanidad Animal CISA INIA/CSIC, Valdeolmos, Madrid, Spain
⨯
Nuria de la Losa,

Roles Investigation, Methodology

Affiliation Department of IMMUNOLOGY, PATHOLOGY AND CONTROL OF INFECTIOUS DISEASES, Centro de Investigación en Sanidad Animal CISA INIA/CSIC, Valdeolmos, Madrid, Spain
⨯
Pedro José Sánchez-Cordón,

Roles Formal analysis, Investigation, Methodology, Validation, Writing – original draft

Affiliation Department of INFECTIOUS DISEASES AND GLOBAL HEALTH, Centro de Investigación en Sanidad Animal CISA INIA/CSIC, Valdeolmos, Madrid, Spain
⨯
Alejandro Brun

Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – review & editing

* E-mail: borrego@inia.csic.es (BB); brun@inia.csic.es (AB)

Affiliation Department of IMMUNOLOGY, PATHOLOGY AND CONTROL OF INFECTIOUS DISEASES, Centro de Investigación en Sanidad Animal CISA INIA/CSIC, Valdeolmos, Madrid, Spain
⨯

The Rift Valley fever (RVF) vaccine candidate 40Fp8 shows an extreme attenuation in IFNARKO mice following intranasal inoculation

Belén Borrego,
Celia Alonso,
Sandra Moreno,
Nuria de la Losa,
Pedro José Sánchez-Cordón,
Alejandro Brun

Published: August 19, 2024
https://doi.org/10.1371/journal.pntd.0012011

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Rift Valley fever virus
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Viral vaccines
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Attenuated vaccines
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Mouse models
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Euthanasia
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Immunohistochemistry techniques
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Inoculation
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