Effects of structurally distinct human HDAC6 and HDAC6/HDAC8 inhibitors against S. mansoni larval and adult worm stages

Roberto Gimmelli; Giuliana Papoff; Fulvio Saccoccia; Cristiana Lalli; Sandra Gemma; Giuseppe Campiani; Giovina Ruberti

doi:10.1371/journal.pntd.0011992

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Open Access

Peer-reviewed

Research Article

Effects of structurally distinct human HDAC6 and HDAC6/HDAC8 inhibitors against S. mansoni larval and adult worm stages

Roberto Gimmelli,

Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – review & editing

Affiliations Institute of Biochemistry and Cell Biology, National Research Council (IBBC-CNR), Adriano Buzzati-Traverso Campus, Monterotondo, Rome, Italy, Dipartimento di Scienze Biochimiche "A. Rossi Fanelli", Sapienza Università di Roma, Roma, Italy
⨯
Giuliana Papoff,

Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – review & editing

Affiliation Institute of Biochemistry and Cell Biology, National Research Council (IBBC-CNR), Adriano Buzzati-Traverso Campus, Monterotondo, Rome, Italy
⨯
Fulvio Saccoccia,

Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – review & editing

Affiliation Institute of Biochemistry and Cell Biology, National Research Council (IBBC-CNR), Adriano Buzzati-Traverso Campus, Monterotondo, Rome, Italy
⨯
Cristiana Lalli,

Roles Data curation, Formal analysis, Investigation, Methodology

Affiliation Institute of Biochemistry and Cell Biology, National Research Council (IBBC-CNR), Adriano Buzzati-Traverso Campus, Monterotondo, Rome, Italy
⨯
Sandra Gemma,

Roles Data curation, Formal analysis, Investigation, Visualization, Writing – review & editing

Affiliation Department of Biotechnology, Chemistry and Pharmacy, University of Siena, Siena, Italy
⨯
Giuseppe Campiani,

Roles Data curation, Formal analysis, Funding acquisition, Writing – review & editing

Affiliation Department of Biotechnology, Chemistry and Pharmacy, University of Siena, Siena, Italy
⨯
Giovina Ruberti

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

* E-mail: giovina.ruberti@cnr.it

Affiliation Institute of Biochemistry and Cell Biology, National Research Council (IBBC-CNR), Adriano Buzzati-Traverso Campus, Monterotondo, Rome, Italy

https://orcid.org/0000-0003-2367-9709

⨯

Effects of structurally distinct human HDAC6 and HDAC6/HDAC8 inhibitors against S. mansoni larval and adult worm stages

Roberto Gimmelli,
Giuliana Papoff,
Fulvio Saccoccia,
Cristiana Lalli,
Sandra Gemma,
Giuseppe Campiani,
Giovina Ruberti

Published: February 28, 2024
https://doi.org/10.1371/journal.pntd.0011992

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Schistosoma mansoni
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Eggs
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Larvae
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Parasitic diseases
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Parasitic life cycles
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Tubulins
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Histones
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