Hepatic macrophages play critical roles in the establishment and growth of hydatid cysts in the liver during Echinococcus granulosus sensu stricto infection

Hui Wang; Qian Yu; Mingkun Wang; Jiao Hou; Maolin Wang; Xuejiao Kang; Xinling Hou; Dewei Li; Zibigu Rousu; Tiemin Jiang; Jing Li; Hao Wen; Chuanshan Zhang

doi:10.1371/journal.pntd.0011746

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Open Access

Peer-reviewed

Research Article

Hepatic macrophages play critical roles in the establishment and growth of hydatid cysts in the liver during Echinococcus granulosus sensu stricto infection

Hui Wang ,

Contributed equally to this work with: Hui Wang, Qian Yu, Mingkun Wang

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Software, Supervision, Writing – original draft, Writing – review & editing

* E-mail: wangh0923@126.com (HWA); dr.wenhao@163.com (HWE); dashan0518@126.com (CZ)

Affiliations State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Clinical Medicine Institute, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China, Basic Medical College, Xinjiang Medical University, Urumqi, Xinjiang, China, Xinjiang Key Laboratory of Echinococcosis, Clinical Medicine Institute, World Health Organization Collaborating Centre on Prevention and Case Management of Echinococcosis, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China
⨯
Qian Yu ,

Contributed equally to this work with: Hui Wang, Qian Yu, Mingkun Wang

Roles Formal analysis, Methodology, Visualization, Writing – original draft

Affiliation Basic Medical College, Xinjiang Medical University, Urumqi, Xinjiang, China
⨯
Mingkun Wang ,

Contributed equally to this work with: Hui Wang, Qian Yu, Mingkun Wang

Roles Formal analysis, Methodology, Software

Affiliation Basic Medical College, Xinjiang Medical University, Urumqi, Xinjiang, China
⨯
Jiao Hou,

Roles Investigation, Resources, Software

Affiliation State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Clinical Medicine Institute, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China
⨯
Maolin Wang,

Roles Investigation, Resources

Affiliations State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Clinical Medicine Institute, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China, Department of Hepatic Hydatid and Hepatobiliary Surgery, Digestive and Vascular Surgery Centre, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China
⨯
Xuejiao Kang,

Roles Visualization

Affiliation Basic Medical College, Xinjiang Medical University, Urumqi, Xinjiang, China
⨯
Xinling Hou,

Roles Methodology

Affiliation Basic Medical College, Xinjiang Medical University, Urumqi, Xinjiang, China
⨯
Dewei Li,

Roles Software

Affiliation Basic Medical College, Xinjiang Medical University, Urumqi, Xinjiang, China
⨯
Zibigu Rousu,

Roles Methodology

Affiliation Basic Medical College, Xinjiang Medical University, Urumqi, Xinjiang, China
⨯
Tiemin Jiang,

Roles Resources

Affiliations State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Clinical Medicine Institute, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China, Department of Hepatic Hydatid and Hepatobiliary Surgery, Digestive and Vascular Surgery Centre, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China
⨯
Jing Li,

Roles Visualization

Affiliation Basic Medical College, Xinjiang Medical University, Urumqi, Xinjiang, China
⨯
Hao Wen ,

Roles Resources, Writing – review & editing

* E-mail: wangh0923@126.com (HWA); dr.wenhao@163.com (HWE); dashan0518@126.com (CZ)

Affiliations State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Clinical Medicine Institute, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China, Xinjiang Key Laboratory of Echinococcosis, Clinical Medicine Institute, World Health Organization Collaborating Centre on Prevention and Case Management of Echinococcosis, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China
⨯
Chuanshan Zhang

Roles Conceptualization, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

* E-mail: wangh0923@126.com (HWA); dr.wenhao@163.com (HWE); dashan0518@126.com (CZ)

Affiliations State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Clinical Medicine Institute, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China, Basic Medical College, Xinjiang Medical University, Urumqi, Xinjiang, China, Xinjiang Key Laboratory of Echinococcosis, Clinical Medicine Institute, World Health Organization Collaborating Centre on Prevention and Case Management of Echinococcosis, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China

https://orcid.org/0000-0002-3241-2224

⨯

Hepatic macrophages play critical roles in the establishment and growth of hydatid cysts in the liver during Echinococcus granulosus sensu stricto infection

Hui Wang,
Qian Yu,
Mingkun Wang,
Jiao Hou,
Maolin Wang,
Xuejiao Kang,
Xinling Hou,
Dewei Li,
Zibigu Rousu,
Tiemin Jiang

Published: November 6, 2023
https://doi.org/10.1371/journal.pntd.0011746

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