Disruption of the inositol phosphorylceramide synthase gene affects Trypanosoma cruzi differentiation and infection capacity

• Nailma S A Dos Santos ,

  Contributed equally to this work with: Nailma S A Dos Santos, Carlos F. Estevez-Castro

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Writing – review & editing

  Affiliation Departamento de Bioquímica e Imunologia, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil

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• Carlos F. Estevez-Castro ,

  Contributed equally to this work with: Nailma S A Dos Santos, Carlos F. Estevez-Castro

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Departamento de Bioquímica e Imunologia, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil

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• Juan P. Macedo,

  Roles Conceptualization, Data curation, Methodology, Writing – review & editing

  Affiliation Departamento de Bioquímica e Imunologia, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil

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• Daniela F. Chame,

  Roles Data curation, Investigation, Methodology

  Affiliation Departamento de Bioquímica e Imunologia, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil

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• Thiago Castro-Gomes,

  Roles Data curation, Formal analysis, Writing – review & editing

  Affiliation Departamento de Parasitologia, Universidade Federal de Minas, Belo Horizonte, Brazil

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• Mariana Santos-Cardoso,

  Roles Investigation, Methodology

  Affiliation Departamento de Bioquímica e Imunologia, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil

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• Gabriela A. Burle-Caldas,

  Roles Formal analysis, Methodology

  Affiliation Departamento de Bioquímica e Imunologia, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil

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• Courtney N. Covington,

  Roles Formal analysis, Methodology

  Affiliation Department of Chemistry and Centre for Global Infectious Disease, Durham University, Durham, United Kingdom

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• Patrick G. Steel,

  Roles Data curation, Supervision

  Affiliation Department of Chemistry and Centre for Global Infectious Disease, Durham University, Durham, United Kingdom

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• Terry K. Smith,

  Roles Data curation, Formal analysis, Writing – review & editing

  Affiliation BSRC School of Biology, Biomolecular Science Building, St Andrews, United Kingdom

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• Paul W. Denny,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Resources, Writing – review & editing

  Affiliation Department of Biosciences and Centre for Global Infectious Diseases, Durham University, Durham, United Kingdom

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• Santuza M. R. Teixeira

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: santuzat@ufmg.br

  Affiliation Departamento de Bioquímica e Imunologia, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil

  https://orcid.org/0000-0002-2588-2842

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