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Open Access
Peer-reviewed
Research Article
Efficacy, safety, and tolerability of albendazole and ivermectin based regimens for the treatment of microfilaraemic loiasis in adult patients in Gabon: A randomized controlled assessor blinded clinical trial
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Rella Zoleko-Manego,
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing
Affiliations Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon, Department of Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine & I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, German Center for Infection Research–Partner Sites Hamburg-Lübeck-Borstel-Riems, Germany
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Ruth Kreuzmair,
Roles Data curation, Investigation, Writing – review & editing
Affiliations Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon, Radboud University Medical Center, Nijmegen, Netherlands
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Luzia Veletzky,
Roles Data curation, Writing – review & editing
Affiliations Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon, Department of Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine & I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, German Center for Infection Research–Partner Sites Hamburg-Lübeck-Borstel-Riems, Germany
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Wilfrid Ndzebe-Ndoumba,
Roles Data curation, Writing – review & editing
Affiliation Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon
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Dorothea Ekoka Mbassi,
Roles Data curation, Investigation, Writing – review & editing
Affiliations Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon, Department of Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine & I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, German Center for Infection Research–Partner Sites Hamburg-Lübeck-Borstel-Riems, Germany
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Dearie G. Okwu,
Roles Data curation, Investigation, Writing – review & editing
Affiliation Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon
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Lia B. Dimessa-Mbadinga-Weyat,
Roles Data curation, Investigation, Writing – review & editing
Affiliation Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon
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Roselyne D. Houtsa-Temgoua,
Roles Data curation, Investigation, Writing – review & editing
Affiliation Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon
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Johannes Mischlinger,
Roles Formal analysis, Visualization, Writing – review & editing
Affiliations Department of Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine & I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, German Center for Infection Research–Partner Sites Hamburg-Lübeck-Borstel-Riems, Germany
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Matthew B. B. McCall,
Roles Investigation, Writing – review & editing
Affiliation Radboud University Medical Center, Nijmegen, Netherlands
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Peter G. Kresmner,
Roles Conceptualization, Methodology, Writing – review & editing
Affiliations Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon, Institute of Tropical Medicine, University of Tübingen, Tübingen, Germany, German Center for Infection Research–Partner Site Tübingen, Germany
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Selidji T. Agnandji,
Roles Data curation, Investigation, Writing – review & editing
Affiliations Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon, Institute of Tropical Medicine, University of Tübingen, Tübingen, Germany
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Betrand Lell,
Roles Data curation, Writing – review & editing
Affiliations Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon, Division of Infectious Diseases and Tropical Medicine, Department of Medicine 1, Medical University of Vienna, Vienna, Austria
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Ayôla A. Adegnika,
Roles Investigation, Writing – review & editing
Affiliations Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon, Institute of Tropical Medicine, University of Tübingen, Tübingen, Germany, German Center for Infection Research–Partner Site Tübingen, Germany
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Ghyslain Mombo-Ngoma,
Roles Conceptualization, Data curation, Investigation, Writing – review & editing
Affiliations Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon, Department of Implementation Research, Bernhard Nocht Institute for Tropical Medicine & I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
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Michael Ramharter
Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing
* E-mail: ramharter@bnitm.de
Affiliations Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon, Department of Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine & I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, German Center for Infection Research–Partner Sites Hamburg-Lübeck-Borstel-Riems, Germany
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Efficacy, safety, and tolerability of albendazole and ivermectin based regimens for the treatment of microfilaraemic loiasis in adult patients in Gabon: A randomized controlled assessor blinded clinical trial
- Rella Zoleko-Manego,
- Ruth Kreuzmair,
- Luzia Veletzky,
- Wilfrid Ndzebe-Ndoumba,
- Dorothea Ekoka Mbassi,
- Dearie G. Okwu,
- Lia B. Dimessa-Mbadinga-Weyat,
- Roselyne D. Houtsa-Temgoua,
- Johannes Mischlinger,
- Matthew B. B. McCall
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- Published: August 28, 2023
- https://doi.org/10.1371/journal.pntd.0011584