Transcriptome profiles of Trypanosoma brucei rhodesiense in Malawi reveal focus specific gene expression profiles associated with pathology

Peter Nambala; Harry Noyes; Joyce Namulondo; Oscar Nyangiri; Vincent Pius Alibu; Barbara Nerima; Annette MacLeod; Enock Matovu; Janelisa Musaya; Julius Mulindwa; on behalf of the TrypanoGEN+ Research Group as Members of the H3Africa Consortium

doi:10.1371/journal.pntd.0011516

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Open Access

Peer-reviewed

Research Article

Transcriptome profiles of Trypanosoma brucei rhodesiense in Malawi reveal focus specific gene expression profiles associated with pathology

Peter Nambala,

Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – original draft

Affiliations Department of Biochemistry and Sports Sciences, College of Natural Sciences, Makerere University, Kampala, Uganda, Kamuzu University of Health Sciences, Malawi-Liverpool-Wellcome Trust Clinical Research Programme, Blantyre, Malawi
⨯
Harry Noyes,

Roles Conceptualization, Formal analysis, Methodology, Writing – review & editing

Affiliation Centre for Genomic Research, University of Liverpool, Liverpool, United Kingdom
⨯
Joyce Namulondo,

Roles Formal analysis

Affiliation Department of Biotechnical and Diagnostic Sciences, College of Veterinary Medicine Animal Resources and Biosecurity, Makerere University, Kampala, Uganda
⨯
Oscar Nyangiri,

Roles Formal analysis

Affiliation Department of Biotechnical and Diagnostic Sciences, College of Veterinary Medicine Animal Resources and Biosecurity, Makerere University, Kampala, Uganda
⨯
Vincent Pius Alibu,

Roles Writing – review & editing

Affiliation Department of Biotechnical and Diagnostic Sciences, College of Veterinary Medicine Animal Resources and Biosecurity, Makerere University, Kampala, Uganda
⨯
Barbara Nerima,

Roles Writing – review & editing

Affiliation Department of Biochemistry and Sports Sciences, College of Natural Sciences, Makerere University, Kampala, Uganda
⨯
Annette MacLeod,

Roles Conceptualization, Funding acquisition, Writing – review & editing

Affiliation Wellcome Centre for Integrative Parasitology, University of Glasgow, Glasgow, United Kingdom
⨯
Enock Matovu,

Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

Affiliation Department of Biotechnical and Diagnostic Sciences, College of Veterinary Medicine Animal Resources and Biosecurity, Makerere University, Kampala, Uganda
⨯
Janelisa Musaya,

Roles Conceptualization, Supervision, Writing – review & editing

Affiliation Kamuzu University of Health Sciences, Malawi-Liverpool-Wellcome Trust Clinical Research Programme, Blantyre, Malawi
⨯
Julius Mulindwa ,

Roles Conceptualization, Formal analysis, Investigation, Methodology, Supervision, Validation, Writing – review & editing

* E-mail: Julius.mulindwa@mak.ac.ug

Affiliation Department of Biochemistry and Sports Sciences, College of Natural Sciences, Makerere University, Kampala, Uganda

https://orcid.org/0000-0002-5419-2760

⨯
on behalf of the TrypanoGEN+ Research Group as Members of the H3Africa Consortium

Transcriptome profiles of Trypanosoma brucei rhodesiense in Malawi reveal focus specific gene expression profiles associated with pathology

Peter Nambala,
Harry Noyes,
Joyce Namulondo,
Oscar Nyangiri,
Vincent Pius Alibu,
Barbara Nerima,
Annette MacLeod,
Enock Matovu,
Janelisa Musaya,
Julius Mulindwa

Published: May 3, 2024
https://doi.org/10.1371/journal.pntd.0011516

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Transcriptome analysis
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Trypanosoma brucei gambiense
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