Epilepsy and nodding syndrome in association with an Onchocerca volvulus infection drive distinct immune profile patterns

• Kathrin Arndts ,

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  * E-mail: kathrin.arndts@ukbonn.de (KA); hoerauf@uni-bonn.de (AH); andrea.winkler@tum.de (ASW)

  ¶‡ KA and JK share first authorship on this work. AH, LEL-H and ASW share last authorship on this work.

  Affiliation Institute of Medical Microbiology, Immunology and Parasitology (IMMIP), University Hospital Bonn (UKB), Bonn, German

  https://orcid.org/0000-0003-1091-4861

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• Josua Kegele ,

  Roles Data curation, Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing

  ¶‡ KA and JK share first authorship on this work. AH, LEL-H and ASW share last authorship on this work.

  Affiliation Hertie Institute for Clinical Brain Research, Department of Neurology and Epileptology, University of Tübingen, Tübingen, Germany

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• Alain S. Massarani,

  Roles Data curation, Formal analysis, Investigation

  Affiliation Institute of Medical Microbiology, Immunology and Parasitology (IMMIP), University Hospital Bonn (UKB), Bonn, German

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• Manuel Ritter,

  Roles Investigation, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Institute of Medical Microbiology, Immunology and Parasitology (IMMIP), University Hospital Bonn (UKB), Bonn, German

  ⨯
• Thomas Wagner,

  Roles Data curation, Formal analysis, Methodology

  Affiliations Center for Pediatric and Adolescent Medicine, University Heidelberg, Heidelberg, Germany, German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, Bonn, Germany, German Center for Infection Research (DZIF), Partner Site Munich, Germany

  ⨯
• Kenneth Pfarr,

  Roles Data curation, Project administration, Supervision, Writing – review & editing

  Affiliations Institute of Medical Microbiology, Immunology and Parasitology (IMMIP), University Hospital Bonn (UKB), Bonn, German, German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, Bonn, Germany

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• Christine Lämmer,

  Roles Formal analysis, Investigation

  Affiliations Institute of Medical Microbiology, Immunology and Parasitology (IMMIP), University Hospital Bonn (UKB), Bonn, German, German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, Bonn, Germany

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• Peter Dörmann,

  Roles Methodology, Resources, Software

  Affiliation Institute of Molecular Physiology and Biotechnology of Plants, University of Bonn, Bonn, Germany

  ⨯
• Helga Peisker,

  Roles Formal analysis, Investigation, Methodology

  Affiliation Institute of Molecular Physiology and Biotechnology of Plants, University of Bonn, Bonn, Germany

  ⨯
• Dirk Menche,

  Roles Formal analysis, Resources

  Affiliation Kekulé Institute of Organic Chemistry and Biochemistry, University of Bonn, Bonn, Germany

  ⨯
• Mazen Al-Bahra,

  Roles Formal analysis, Investigation, Resources

  Affiliation Kekulé Institute of Organic Chemistry and Biochemistry, University of Bonn, Bonn, Germany

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• Clarissa Prazeres da Costa,

  Roles Conceptualization, Funding acquisition, Project administration

  Affiliations German Center for Infection Research (DZIF), Partner Site Munich, Germany, Institute of Medical Microbiology, Immunology and Hygiene, Technical University of Munich, Munich, Germany, Center for Global Health, School of Medicine, Technical University of Munich, Munich, Germany

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• Erich Schmutzhard,

  Roles Project administration, Supervision, Writing – review & editing

  Affiliation Department of Neurology, Medical University Innsbruck, Innsbruck, Austria

  ⨯
• William Matuja,

  Roles Project administration, Resources, Supervision

  Affiliation Department of Neurology, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania

  ⨯
• Achim Hoerauf ,

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing

  * E-mail: kathrin.arndts@ukbonn.de (KA); hoerauf@uni-bonn.de (AH); andrea.winkler@tum.de (ASW)

  ¶‡ KA and JK share first authorship on this work. AH, LEL-H and ASW share last authorship on this work.

  Affiliations Institute of Medical Microbiology, Immunology and Parasitology (IMMIP), University Hospital Bonn (UKB), Bonn, German, German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, Bonn, Germany, German-West African Centre for Global Health and Pandemic Prevention (G-WAC), Partner Site Bonn, Bonn, Germany

  ⨯
• Laura E. Layland-Heni ,

  Roles Investigation, Project administration, Supervision, Writing – original draft, Writing – review & editing

  ¶‡ KA and JK share first authorship on this work. AH, LEL-H and ASW share last authorship on this work.

  Affiliations Institute of Medical Microbiology, Immunology and Parasitology (IMMIP), University Hospital Bonn (UKB), Bonn, German, German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, Bonn, Germany

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•  [ ... ],
• Andrea S. Winkler

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: kathrin.arndts@ukbonn.de (KA); hoerauf@uni-bonn.de (AH); andrea.winkler@tum.de (ASW)

  ¶‡ KA and JK share first authorship on this work. AH, LEL-H and ASW share last authorship on this work.

  Affiliations Center for Global Health, School of Medicine, Technical University of Munich, Munich, Germany, Department of Neurology, Technical University of Munich, Munich, Germany, Department of Community Medicine and Global Health, Institute of Health and Society, University of Oslo, Oslo, Norway, Department of Global Health and Social Medicine, Harvard Medical School, Boston, Massachusetts, USA

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