TLR3 activation by Clonorchis sinensis infection alleviates the fluke-induced liver fibrosis

Yuru Wang; Pengtao Gong; Xuancheng Zhang; Xiaocen Wang; Xu Zhang; Nan Zhang; Yanhui Yu; Yeting Ma; Haoyang Zhang; Xichen Zhang; Xin Li; Jianhua Li

doi:10.1371/journal.pntd.0011325

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Open Access

Peer-reviewed

Research Article

TLR3 activation by Clonorchis sinensis infection alleviates the fluke-induced liver fibrosis

Yuru Wang ,

Contributed equally to this work with: Yuru Wang, Pengtao Gong

Roles Formal analysis, Investigation, Writing – original draft

Affiliation State Key Laboratory for Zoonotic Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun, China
⨯
Pengtao Gong ,

Contributed equally to this work with: Yuru Wang, Pengtao Gong

Roles Writing – review & editing

Affiliation State Key Laboratory for Zoonotic Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun, China
⨯
Xuancheng Zhang,

Roles Investigation

Affiliation State Key Laboratory for Zoonotic Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun, China
⨯
Xiaocen Wang,

Roles Writing – original draft

Affiliation State Key Laboratory for Zoonotic Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun, China
⨯
Xu Zhang,

Roles Formal analysis

Affiliation State Key Laboratory for Zoonotic Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun, China
⨯
Nan Zhang,

Roles Methodology

Affiliation State Key Laboratory for Zoonotic Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun, China
⨯
Yanhui Yu,

Roles Methodology

Affiliation State Key Laboratory for Zoonotic Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun, China
⨯
Yeting Ma,

Roles Formal analysis

Affiliation State Key Laboratory for Zoonotic Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun, China
⨯
Haoyang Zhang,

Roles Methodology

Affiliation State Key Laboratory for Zoonotic Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun, China
⨯
Xichen Zhang,

Roles Funding acquisition, Writing – review & editing

Affiliation State Key Laboratory for Zoonotic Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun, China
⨯
Xin Li ,

Roles Conceptualization

* E-mail: jlulixin0928@163.com (X.L); jianhuali7207@163.com (J.L)

Affiliation State Key Laboratory for Zoonotic Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun, China
⨯
Jianhua Li

Roles Conceptualization, Funding acquisition

* E-mail: jlulixin0928@163.com (X.L); jianhuali7207@163.com (J.L)

Affiliation State Key Laboratory for Zoonotic Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun, China

https://orcid.org/0000-0003-3319-5206

⨯

TLR3 activation by Clonorchis sinensis infection alleviates the fluke-induced liver fibrosis

Yuru Wang,
Pengtao Gong,
Xuancheng Zhang,
Xiaocen Wang,
Xu Zhang,
Nan Zhang,
Yanhui Yu,
Yeting Ma,
Haoyang Zhang,
Xichen Zhang

Published: May 11, 2023
https://doi.org/10.1371/journal.pntd.0011325

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