Treatment with benznidazole and pentoxifylline regulates microRNA transcriptomic profile in a murine model of Chagas chronic cardiomyopathy

• Priscila Silva Grijó Farani,

  Roles Data curation, Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing

  Affiliations Real-Time PCR Platform RPT09A, Laboratory of Molecular Virology and Parasitology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil, Laboratory of Biology of the Interactions, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil

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• Beatriz Iandra da Silva Ferreira,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Real-Time PCR Platform RPT09A, Laboratory of Molecular Virology and Parasitology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil

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• Khodeza Begum,

  Roles Formal analysis, Writing – review & editing

  Affiliation Border Biomedical Research Center, Department of Biological Sciences, University of Texas at El Paso, El Paso, Texas, United States of America

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• Glaucia Vilar-Pereira,

  Roles Investigation, Writing – review & editing

  Affiliation Laboratory of Biology of the Interactions, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil

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• Isabela Resende Pereira,

  Roles Investigation, Writing – review & editing

  Affiliation Laboratory of Biology of the Interactions, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil

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• Edith A. Fernández-Figueroa,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Computational and Integrative Genomics, Instituto Nacional de Medicina Genómica, Arenal Tepepan, Mexico City, Mexico

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• Roberto Alejandro Cardenas-Ovando,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Computational and Integrative Genomics, Instituto Nacional de Medicina Genómica, Arenal Tepepan, Mexico City, Mexico

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• Igor C. Almeida,

  Roles Formal analysis, Visualization, Writing – review & editing

  Affiliation Border Biomedical Research Center, Department of Biological Sciences, University of Texas at El Paso, El Paso, Texas, United States of America

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• Sourav Roy,

  Roles Data curation, Formal analysis, Methodology, Validation, Writing – review & editing

  Affiliation Border Biomedical Research Center, Department of Biological Sciences, University of Texas at El Paso, El Paso, Texas, United States of America

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• Joseli Lannes-Vieira,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Validation, Visualization, Writing – review & editing

  Affiliation Laboratory of Biology of the Interactions, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil

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• Otacilio Cruz Moreira

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – review & editing

  * E-mail: otacilio@ioc.fiocruz.br

  Affiliation Real-Time PCR Platform RPT09A, Laboratory of Molecular Virology and Parasitology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil

  https://orcid.org/0000-0002-5340-8697

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