A general framework to support cost-efficient fecal egg count methods and study design choices for large-scale STH deworming programs–monitoring of therapeutic drug efficacy as a case study

• Luc E. Coffeng ,

  Contributed equally to this work with: Luc E. Coffeng, Johnny Vlaminck

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: l.coffeng@erasmusmc.nl (LEC); bruno.levecke@ugent.be (BL)

  Affiliation Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands

  https://orcid.org/0000-0002-4425-2264

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• Johnny Vlaminck ,

  Contributed equally to this work with: Luc E. Coffeng, Johnny Vlaminck

  Roles Data curation, Formal analysis, Investigation, Methodology, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Translational Physiology, Infectiology and Public Health, Ghent University, Merelbeke, Belgium

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• Piet Cools,

  Roles Data curation, Formal analysis, Investigation, Methodology, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Diagnostic Sciences, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium

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• Matthew Denwood,

  Roles Software, Validation, Writing – review & editing

  Affiliation Department of Veterinary and Animal Sciences, University of Copenhagen, Denmark

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• Marco Albonico,

  Roles Conceptualization, Funding acquisition, Resources, Writing – review & editing

  Affiliation National Health System, Turin, Italy

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• Shaali M. Ame,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Laboratory Division, Public Health Laboratory-Ivo de Carneri, Chake Chake, United Republic of Tanzania

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• Mio Ayana,

  Roles Investigation, Methodology, Resources, Writing – review & editing

  Affiliations Department of Diagnostic Sciences, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium, Jimma University Institute of Health, Jimma University, Jimma, Ethiopia

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• Daniel Dana,

  Roles Investigation, Writing – review & editing

  Affiliations Department of Diagnostic Sciences, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium, Jimma University Institute of Health, Jimma University, Jimma, Ethiopia

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• Giuseppe Cringoli,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Veterinary Medicine and Animal Production, University of Naples Federico II, Naples, Italy

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• Sake J. de Vlas,

  Roles Conceptualization, Supervision, Validation, Writing – review & editing

  Affiliation Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands

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• Alan Fenwick,

  Roles Funding acquisition, Resources, Writing – review & editing

  Affiliation Schistosomiasis Control Initiative, Department of Infectious Disease Epidemiology, St Mary’s Campus, Imperial College London, London, United Kingdom

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• Michael French,

  Roles Funding acquisition, Resources, Writing – review & editing

  Affiliations Schistosomiasis Control Initiative, Department of Infectious Disease Epidemiology, St Mary’s Campus, Imperial College London, London, United Kingdom, RTI International, Washington District of Columbia, United States of America

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• Adama Kazienga,

  Roles Data curation, Formal analysis, Writing – review & editing

  Affiliation Department of Translational Physiology, Infectiology and Public Health, Ghent University, Merelbeke, Belgium

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• Jennifer Keiser,

  Roles Conceptualization, Funding acquisition, Methodology, Writing – review & editing

  Affiliations Swiss Tropical and Public Health Institute, Allschwil, Switzerland, University of Basel, Basel, Switzerland

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• Stefanie Knopp,

  Roles Resources, Writing – review & editing

  Affiliations Swiss Tropical and Public Health Institute, Allschwil, Switzerland, University of Basel, Basel, Switzerland

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• Gemechu Leta,

  Roles Funding acquisition, Resources, Writing – review & editing

  Affiliation Ethiopian Public Health Institute, Addis Ababa, Ethiopia

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• Leonardo F. Matoso,

  Roles Investigation, Writing – review & editing

  Affiliations Laboratory of Molecular and Cellular Immunology, Research Center René Rachou—FIOCRUZ, Belo Horizonte, Brazil, Nursing school, Federal University of Minas Gerais, Belo Horizonte, Brazil

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• Maria P. Maurelli,

  Roles Resources, Writing – review & editing

  Affiliation Department of Veterinary Medicine and Animal Production, University of Naples Federico II, Naples, Italy

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• Antonio Montresor,

  Roles Resources, Writing – review & editing

  Affiliation Department of Control of Neglected Tropical Diseases, World Health Organization, Geneva, Switzerland

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• Greg Mirams,

  Roles Resources, Software, Writing – review & editing

  Affiliation Techion Group Ltd, Dunedin, New Zealand

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• Zeleke Mekonnen,

  Roles Resources, Writing – review & editing

  Affiliation Jimma University Institute of Health, Jimma University, Jimma, Ethiopia

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• Rodrigo Corrêa-Oliveira,

  Roles Resources, Writing – review & editing

  Affiliation Laboratory of Molecular and Cellular Immunology, Research Center René Rachou—FIOCRUZ, Belo Horizonte, Brazil

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• Simone A. Pinto,

  Roles Investigation, Writing – review & editing

  Affiliation Laboratory of Molecular and Cellular Immunology, Research Center René Rachou—FIOCRUZ, Belo Horizonte, Brazil

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• Laura Rinaldi,

  Roles Resources, Writing – review & editing

  Affiliation Department of Veterinary Medicine and Animal Production, University of Naples Federico II, Naples, Italy

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• Somphou Sayasone,

  Roles Resources, Writing – review & editing

  Affiliation Lao Tropical and Public Health Institute, Ministry of Health, Vientiane, Lao People’s Democratic Republic

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• Peter Steinmann,

  Roles Resources, Writing – review & editing

  Affiliations Swiss Tropical and Public Health Institute, Allschwil, Switzerland, University of Basel, Basel, Switzerland

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• Eurion Thomas,

  Roles Resources, Software, Writing – review & editing

  Affiliation Techion Group Ltd, Aberystwyth, United Kingdom

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• Jozef Vercruysse,

  Roles Conceptualization, Funding acquisition, Writing – review & editing

  Affiliation Department of Translational Physiology, Infectiology and Public Health, Ghent University, Merelbeke, Belgium

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•  [ ... ],
• Bruno Levecke

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: l.coffeng@erasmusmc.nl (LEC); bruno.levecke@ugent.be (BL)

  Affiliation Department of Translational Physiology, Infectiology and Public Health, Ghent University, Merelbeke, Belgium

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