Genomic and phenotypic analyses suggest moderate fitness differences among Zika virus lineages

• Glenn Oliveira ,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing

  ¶‡ GO and CBFV share first authorship on this work. NDG and KGA are joint senior authors on this work.

  Affiliation Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, California, United States of America

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• Chantal B. F. Vogels ,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  ¶‡ GO and CBFV share first authorship on this work. NDG and KGA are joint senior authors on this work.

  Affiliation Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, Connecticut, United States of America

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• Ashley Zolfaghari,

  Roles Data curation, Investigation, Writing – original draft

  Affiliation Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, California, United States of America

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• Sharada Saraf,

  Roles Investigation

  Affiliation Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, California, United States of America

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• Raphaelle Klitting,

  Roles Methodology, Supervision

  Affiliation Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, California, United States of America

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• James Weger-Lucarelli,

  Roles Methodology, Resources, Supervision

  Affiliation Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, Virginia, United States of America

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• Karla P. Leon,

  Roles Investigation

  Affiliation Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, California, United States of America

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• Carlos O. Ontiveros,

  Roles Investigation

  Affiliation Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, California, United States of America

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• Rimjhim Agarwal,

  Roles Investigation

  Affiliation Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, California, United States of America

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• Konstantin A. Tsetsarkin,

  Roles Methodology, Resources

  Affiliation Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

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• Eva Harris,

  Roles Methodology, Resources

  Affiliation Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, California, United States of America

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• Gregory D. Ebel,

  Roles Methodology, Resources

  Affiliation Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, United States of America

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• Shirlee Wohl,

  Roles Supervision, Writing – review & editing

  Affiliation Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, California, United States of America

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• Nathan D. Grubaugh ,

  Roles Conceptualization, Funding acquisition, Methodology, Supervision

  * E-mail: nathan.grubaugh@yale.edu (NDG); andersen@scripps.edu(KGA)

  ¶‡ GO and CBFV share first authorship on this work. NDG and KGA are joint senior authors on this work.

  Affiliation Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, Connecticut, United States of America

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• Kristian G. Andersen

  Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

  * E-mail: nathan.grubaugh@yale.edu (NDG); andersen@scripps.edu(KGA)

  ¶‡ GO and CBFV share first authorship on this work. NDG and KGA are joint senior authors on this work.

  Affiliation Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, California, United States of America

  https://orcid.org/0000-0001-6431-5982

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