Congenital Rift Valley fever in Sprague Dawley rats is associated with diffuse infection and pathology of the placenta

Cynthia M. McMillen; Devin A. Boyles; Stefan G. Kostadinov; Ryan M. Hoehl; Madeline M. Schwarz; Joseph R. Albe; Matthew J. Demers; Amy L. Hartman

doi:10.1371/journal.pntd.0010898

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Open Access

Peer-reviewed

Research Article

Congenital Rift Valley fever in Sprague Dawley rats is associated with diffuse infection and pathology of the placenta

Cynthia M. McMillen,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft

Affiliations Center for Vaccine Research, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Department of Infectious Diseases and Microbiology, University of Pittsburgh School of Public Health, Pittsburgh, Pennsylvania, United States of America
⨯
Devin A. Boyles,

Roles Data curation, Formal analysis, Investigation, Methodology, Visualization

Affiliation Center for Vaccine Research, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
Stefan G. Kostadinov,

Roles Formal analysis

Affiliation Department of Pathology, Magee Women’s Hospital of the University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States of America
⨯
Ryan M. Hoehl,

Roles Data curation, Investigation, Methodology

Affiliation Center for Vaccine Research, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
Madeline M. Schwarz,

Roles Data curation, Investigation, Methodology

Affiliations Center for Vaccine Research, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Department of Infectious Diseases and Microbiology, University of Pittsburgh School of Public Health, Pittsburgh, Pennsylvania, United States of America
⨯
Joseph R. Albe,

Roles Data curation, Investigation, Methodology

Affiliations Center for Vaccine Research, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Department of Infectious Diseases and Microbiology, University of Pittsburgh School of Public Health, Pittsburgh, Pennsylvania, United States of America
⨯
Matthew J. Demers,

Roles Data curation, Investigation, Methodology

Affiliation Center for Vaccine Research, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
Amy L. Hartman

Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft

* E-mail: hartman2@pitt.edu

Affiliations Center for Vaccine Research, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Department of Infectious Diseases and Microbiology, University of Pittsburgh School of Public Health, Pittsburgh, Pennsylvania, United States of America

https://orcid.org/0000-0002-0857-2973

⨯

Congenital Rift Valley fever in Sprague Dawley rats is associated with diffuse infection and pathology of the placenta

Cynthia M. McMillen,
Devin A. Boyles,
Stefan G. Kostadinov,
Ryan M. Hoehl,
Madeline M. Schwarz,
Joseph R. Albe,
Matthew J. Demers,
Amy L. Hartman

Published: October 31, 2022
https://doi.org/10.1371/journal.pntd.0010898

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Rift Valley fever virus
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Placenta
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Hemorrhage
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Necrosis
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Inflammation
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Uterus
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Decidua
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Trophoblasts
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