Vaccine-linked chemotherapy with a low dose of benznidazole plus a bivalent recombinant protein vaccine prevents the development of cardiac fibrosis caused by Trypanosoma cruzi in chronically-infected BALB/c mice

• Victor Manuel Dzul-Huchim,

  Roles Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft

  Affiliation Laboratorio de Parasitología, Centro de Investigaciones Regionales Dr. Hideyo Noguchi, Universidad Autónoma de Yucatán, Mérida, Yucatán, México

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• Maria Jesus Ramirez-Sierra,

  Roles Resources

  Affiliation Laboratorio de Parasitología, Centro de Investigaciones Regionales Dr. Hideyo Noguchi, Universidad Autónoma de Yucatán, Mérida, Yucatán, México

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• Pedro Pablo Martinez-Vega,

  Roles Resources

  Affiliation Laboratorio de Parasitología, Centro de Investigaciones Regionales Dr. Hideyo Noguchi, Universidad Autónoma de Yucatán, Mérida, Yucatán, México

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• Miguel Enrique Rosado-Vallado,

  Roles Funding acquisition, Supervision

  Affiliation Laboratorio de Parasitología, Centro de Investigaciones Regionales Dr. Hideyo Noguchi, Universidad Autónoma de Yucatán, Mérida, Yucatán, México

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• Victor Ermilo Arana-Argaez,

  Roles Methodology, Writing – review & editing

  Affiliation Laboratorio de Farmacología, Facultad de Química, Universidad Autónoma de Yucatán, Mérida, Yucatán, México

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• Jaime Ortega-Lopez,

  Roles Resources, Writing – review & editing

  Affiliation Departamento de Biotecnología y Bioingeniería, Centro de Investigación y Estudios Avanzados del Instituto Politécnico Nacional, Ciudad de México, México

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• Fabian Gusovsky,

  Roles Resources, Writing – review & editing

  Affiliation Eisai, Inc., Eisai Inc, Andover, Massachusetts, United States of America

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• Eric Dumonteil,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliation Department of Tropical Medicine, School of Public Health and Tropical Medicine, and Vector-Borne and Infectious Disease Research Center, Tulane University, New Orleans, Los Angeles, United States of America

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• Julio Vladimir Cruz-Chan,

  Roles Conceptualization, Formal analysis, Supervision, Writing – review & editing

  Affiliation Laboratorio de Parasitología, Centro de Investigaciones Regionales Dr. Hideyo Noguchi, Universidad Autónoma de Yucatán, Mérida, Yucatán, México

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• Peter Hotez,

  Roles Funding acquisition, Project administration, Supervision, Writing – review & editing

  Affiliations Texas Children’s Center for Vaccine Development, Departments of Pediatrics and Molecular Virology & Microbiology, Baylor College of Medicine, Houston, Texas, United States of America, Department of Biology, Baylor University, Waco, Texas, United States of America

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• María Elena Bottazzi,

  Roles Funding acquisition, Project administration, Supervision, Writing – review & editing

  Affiliations Texas Children’s Center for Vaccine Development, Departments of Pediatrics and Molecular Virology & Microbiology, Baylor College of Medicine, Houston, Texas, United States of America, Department of Biology, Baylor University, Waco, Texas, United States of America

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• Liliana Estefania Villanueva-Lizama

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Visualization, Writing – review & editing

  * E-mail: liliana.villanueva@correo.uady.mx

  Affiliation Laboratorio de Parasitología, Centro de Investigaciones Regionales Dr. Hideyo Noguchi, Universidad Autónoma de Yucatán, Mérida, Yucatán, México

  https://orcid.org/0000-0002-1848-2584

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