A high-dose inoculum size results in persistent viral infection and arthritis in mice infected with chikungunya virus

• Yue Zhang,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Writing – original draft, Writing – review & editing

  Affiliations Mucosal Immunity Research Group, State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China, University of Chinese Academy of Sciences, Beijing, China

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• Hu Yan,

  Roles Formal analysis, Investigation, Methodology

  Affiliations Mucosal Immunity Research Group, State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China, University of Chinese Academy of Sciences, Beijing, China

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• Xian Li,

  Roles Data curation, Investigation

  Affiliations Mucosal Immunity Research Group, State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China, University of Chinese Academy of Sciences, Beijing, China

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• Dihan Zhou,

  Roles Funding acquisition, Investigation, Methodology

  Affiliation Mucosal Immunity Research Group, State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China

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• Maohua Zhong,

  Roles Funding acquisition, Methodology

  Affiliation Mucosal Immunity Research Group, State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China

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• Jingyi Yang,

  Roles Funding acquisition, Investigation, Methodology

  Affiliations Mucosal Immunity Research Group, State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China, Vaccine and Immunology Research Center, Translational Medical Research Institute, Shanghai Public Health Clinical Center, Fudan University, Shanghai, China

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• Bali Zhao,

  Roles Investigation, Methodology

  Affiliations Mucosal Immunity Research Group, State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China, Vaccine and Immunology Research Center, Translational Medical Research Institute, Shanghai Public Health Clinical Center, Fudan University, Shanghai, China

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• Xuxu Fan,

  Roles Investigation, Methodology

  Affiliations Mucosal Immunity Research Group, State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China, University of Chinese Academy of Sciences, Beijing, China

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• Jun Fan,

  Roles Formal analysis, Methodology

  Affiliation Department of Pathology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

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• Jiayi Shu,

  Roles Methodology

  Affiliation Vaccine and Immunology Research Center, Translational Medical Research Institute, Shanghai Public Health Clinical Center, Fudan University, Shanghai, China

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• Mengji Lu,

  Roles Writing – review & editing

  Affiliation Institute for Virology, University Hospital of Essen, University of Duisburg-Essen, Essen, Germany

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• Xia Jin,

  Roles Funding acquisition, Writing – review & editing

  Affiliation Vaccine and Immunology Research Center, Translational Medical Research Institute, Shanghai Public Health Clinical Center, Fudan University, Shanghai, China

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• Ejuan Zhang ,

  Roles Conceptualization, Funding acquisition, Writing – original draft, Writing – review & editing

  * E-mail: zhangejuan@whu.edu.cn (EZ); yanhuimin@shphc.org.cn (HY)

  Affiliations Mucosal Immunity Research Group, State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China, Medical Science Research Center, Zhongnan Hospital of Wuhan University, Wuhan, China

  https://orcid.org/0000-0003-2421-6749

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• Huimin Yan

  Roles Conceptualization, Funding acquisition, Writing – review & editing

  * E-mail: zhangejuan@whu.edu.cn (EZ); yanhuimin@shphc.org.cn (HY)

  Affiliations Mucosal Immunity Research Group, State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China, Vaccine and Immunology Research Center, Translational Medical Research Institute, Shanghai Public Health Clinical Center, Fudan University, Shanghai, China

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