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Open Access
Peer-reviewed
Research Article
A standardised Phase III clinical trial framework to assess therapeutic interventions for Lassa fever
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Adebola Tolulope Olayinka ,
Contributed equally to this work with: Adebola Tolulope Olayinka, Josephine Bourner
Roles Conceptualization, Investigation, Methodology, Project administration, Writing – review & editing
¶‡ These authors share first authorship on this work.
Affiliation Nigeria Centre for Disease Control, Abuja, Nigeria
⨯ -
Josephine Bourner ,
Contributed equally to this work with: Adebola Tolulope Olayinka, Josephine Bourner
Roles Data curation, Formal analysis, Methodology, Project administration, Visualization, Writing – original draft, Writing – review & editing
* E-mail: josephine.bourner@ndm.ox.ac.uk
¶‡ These authors share first authorship on this work.
Affiliation Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom
⨯ -
George O. Akpede,
Roles Investigation, Writing – review & editing
Affiliation Irrua Specialist Teaching Hospital, Irrua, Edo, Nigeria
⨯ -
Joseph Okoeguale,
Roles Investigation, Writing – review & editing
Affiliation Irrua Specialist Teaching Hospital, Irrua, Edo, Nigeria
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Chukwuyem Abejegah,
Roles Investigation, Writing – review & editing
Affiliation Federal Medical Center, Owo, Ondo State, Nigeria
⨯ -
Nnennaya A. Ajayi,
Roles Investigation, Writing – review & editing
Affiliation Alex Ekwueme Federal University Teaching Hospital, Abakaliki, Nigeria
⨯ -
Christian Akude,
Roles Investigation, Writing – review & editing
Affiliation Bingham University Teaching Hospital, Jos, Nigeria
⨯ -
Oluwafemi Ayodeji,
Roles Investigation, Writing – review & editing
Affiliation Federal Medical Center, Owo, Ondo State, Nigeria
⨯ -
Daniel G. Bausch,
Roles Investigation, Writing – review & editing
Affiliations UK Public Health Rapid Support Team, Public Health England, London, United Kingdom, London School of Hygiene & Tropical Medicine, London, United Kingdom
⨯ -
Hilde de Clerck,
Roles Investigation, Writing – review & editing
Affiliation Médecins sans Frontières, Brussels, Belgium
⨯ -
Chioma Dan-Nwafor,
Roles Investigation, Writing – review & editing
Affiliation Nigeria Centre for Disease Control, Abuja, Nigeria
⨯ -
Jake Dunning,
Roles Investigation, Writing – review & editing
Affiliations Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom, National Infection Service, Public Health England, London, United Kingdom
⨯ -
Cyril Erameh,
Roles Investigation, Writing – review & editing
Affiliation Irrua Specialist Teaching Hospital, Irrua, Edo, Nigeria
⨯ -
Justus Ndulue Eze,
Roles Investigation, Writing – review & editing
Affiliation Alex Ekwueme Federal University Teaching Hospital, Abakaliki, Nigeria
⨯ - Pierre Formenty,
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Annelies Gillesen,
Roles Investigation, Writing – review & editing
Affiliation Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom
⨯ -
Sulaiman Jalloh,
Roles Investigation, Writing – review & editing
Affiliation Ola During Children’s Hospital, Freetown, Sierra Leone
⨯ -
Marie Jaspard,
Roles Investigation, Writing – review & editing
Affiliations The Alliance for International Medical Action (ALIMA), Dakar, Senegal, Institut Nationale de la Santé et de la Recherche Medicale (Inserm), Infectious Diseases in Low Income Contries, Unit 1219, Bordeaux, France
⨯ -
Tolulope Jegede,
Roles Investigation, Writing – review & editing
Affiliation Federal Medical Center, Owo, Ondo State, Nigeria
⨯ -
Jacob Maikere,
Roles Investigation, Writing – review & editing
Affiliation Médecins sans Frontières, Brussels, Belgium
⨯ -
Denis Malvy,
Roles Investigation, Writing – review & editing
Affiliations The Alliance for International Medical Action (ALIMA), Dakar, Senegal, Institut Nationale de la Santé et de la Recherche Medicale (Inserm), Infectious Diseases in Low Income Contries, Unit 1219, Bordeaux, France
⨯ -
Ephraim Ogbaini-Emovon,
Roles Investigation, Writing – review & editing
Affiliation Irrua Specialist Teaching Hospital, Irrua, Edo, Nigeria
⨯ -
Olalekan Ezekial Ojo,
Roles Investigation, Writing – review & editing
Affiliation Federal Medical Center, Owo, Ondo State, Nigeria
⨯ -
Sylvanus Okogbenin,
Roles Investigation, Writing – review & editing
Affiliation Irrua Specialist Teaching Hospital, Irrua, Edo, Nigeria
⨯ - Kwame O’Neill,
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Maria-Lauretta Orji,
Roles Investigation, Writing – review & editing
Affiliation Alex Ekwueme Federal University Teaching Hospital, Abakaliki, Nigeria
⨯ -
Sampson Omagbemi Owhin,
Roles Investigation, Writing – review & editing
Affiliation Federal Medical Center, Owo, Ondo State, Nigeria
⨯ -
Michael Ramharter,
Roles Investigation, Writing – review & editing
Affiliations Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany, Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
⨯ -
Robert J. Samuels,
Roles Investigation, Writing – review & editing
Affiliation Kenema Government Hospital, Kenema, Sierra Leone
⨯ -
Nathan Shehu,
Roles Investigation, Writing – review & editing
Affiliation Jos University Teaching Hospital, Jos, Plateau State, Nigeria
⨯ -
Laura Merson,
Roles Methodology, Writing – review & editing
Affiliation Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom
⨯ -
Alex Paddy Salam,
Roles Methodology, Writing – review & editing
Affiliation Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom
⨯ -
Nzelle Delphine Kayem,
Roles Investigation, Methodology, Writing – review & editing
Affiliation Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom
⨯ -
Peter Horby,
Roles Conceptualization, Supervision, Writing – review & editing
Affiliation Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom
⨯ -
Chikwe Ihekweazu,
Roles Conceptualization, Supervision, Writing – review & editing
Affiliation Nigeria Centre for Disease Control, Abuja, Nigeria
⨯ - [ ... ],
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Piero Olliaro
Roles Conceptualization, Methodology, Supervision, Writing – review & editing
Affiliation Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom
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A standardised Phase III clinical trial framework to assess therapeutic interventions for Lassa fever
- Adebola Tolulope Olayinka,
- Josephine Bourner,
- George O. Akpede,
- Joseph Okoeguale,
- Chukwuyem Abejegah,
- Nnennaya A. Ajayi,
- Christian Akude,
- Oluwafemi Ayodeji,
- Daniel G. Bausch,
- Hilde de Clerck
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- Published: January 6, 2022
- https://doi.org/10.1371/journal.pntd.0010089