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Open Access
Peer-reviewed
Research Article
Chalcones identify cTXNPx as a potential antileishmanial drug target
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Douglas O. Escrivani,
Roles Conceptualization, Formal analysis, Investigation, Writing – original draft
Affiliations Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil, Department of Chemistry, Durham University, Science Laboratories, South Road, Durham, United Kingdom
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Rebecca L. Charlton,
Roles Formal analysis, Investigation, Writing – original draft
Affiliations Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil, Department of Chemistry, Durham University, Science Laboratories, South Road, Durham, United Kingdom
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Marjolly B. Caruso,
Roles Conceptualization, Formal analysis, Investigation, Writing – original draft
Affiliation Instituto de Bioquímica Médica Leopoldo de Meis (IBqM), Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
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Gabriela A. Burle-Caldas,
Roles Conceptualization, Formal analysis, Investigation, Writing – original draft
Affiliation Department of Biosciences, Durham University, Science Laboratories, South Road, Durham, United Kingdom
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Maria Paula G. Borsodi,
Roles Conceptualization, Formal analysis, Investigation, Writing – original draft
Affiliation Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
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Russolina B. Zingali,
Roles Supervision
Affiliation Instituto de Bioquímica Médica Leopoldo de Meis (IBqM), Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
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Natalia Arruda-Costa,
Roles Formal analysis, Investigation
Affiliation Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
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Marcos V. Palmeira-Mello,
Roles Formal analysis, Methodology
Affiliation Faculdade de Farmácia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
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Jéssica B. de Jesus,
Roles Formal analysis, Methodology
Affiliation Faculdade de Farmácia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
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Alessandra M. T. Souza,
Roles Supervision
Affiliation Faculdade de Farmácia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
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Bárbara Abrahim-Vieira,
Roles Supervision
Affiliation Faculdade de Farmácia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
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Stefanie Freitag-Pohl,
Roles Investigation, Methodology
Affiliation Department of Chemistry, Durham University, Science Laboratories, South Road, Durham, United Kingdom
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Ehmke Pohl,
Roles Formal analysis, Investigation, Methodology, Supervision
Affiliations Department of Chemistry, Durham University, Science Laboratories, South Road, Durham, United Kingdom, Department of Biosciences, Durham University, Science Laboratories, South Road, Durham, United Kingdom
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Paul W. Denny,
Roles Conceptualization, Formal analysis, Supervision, Writing – original draft, Writing – review & editing
Affiliation Department of Biosciences, Durham University, Science Laboratories, South Road, Durham, United Kingdom
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Bartira Rossi-Bergmann ,
Roles Conceptualization, Formal analysis, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing
* E-mail: bartira@biof.ufrj.br (BR-B); p.g.steel@durham.ac.uk (PGS)
Affiliation Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
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Patrick G. Steel
Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing
* E-mail: bartira@biof.ufrj.br (BR-B); p.g.steel@durham.ac.uk (PGS)
Affiliation Department of Chemistry, Durham University, Science Laboratories, South Road, Durham, United Kingdom
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Chalcones identify cTXNPx as a potential antileishmanial drug target
- Douglas O. Escrivani,
- Rebecca L. Charlton,
- Marjolly B. Caruso,
- Gabriela A. Burle-Caldas,
- Maria Paula G. Borsodi,
- Russolina B. Zingali,
- Natalia Arruda-Costa,
- Marcos V. Palmeira-Mello,
- Jéssica B. de Jesus,
- Alessandra M. T. Souza
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- Published: November 15, 2021
- https://doi.org/10.1371/journal.pntd.0009951