Rationalizing the design of a broad coverage Shigella vaccine based on evaluation of immunological cross-reactivity among S. flexneri serotypes

• Francesco Citiulo ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  * E-mail: francesco.x.citiulo@gsk.com

  Affiliation GSK Vaccines Institute for Global Health S.r.l. (GVGH), Siena, Italy

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• Francesca Necchi,

  Roles Data curation, Investigation, Methodology, Supervision, Writing – review & editing

  Affiliation GSK Vaccines Institute for Global Health S.r.l. (GVGH), Siena, Italy

  https://orcid.org/0000-0003-2122-9480

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• Francesca Mancini,

  Roles Investigation, Methodology, Validation, Writing – review & editing

  Affiliation GSK Vaccines Institute for Global Health S.r.l. (GVGH), Siena, Italy

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• Omar Rossi,

  Roles Data curation, Investigation, Validation, Writing – review & editing

  Affiliation GSK Vaccines Institute for Global Health S.r.l. (GVGH), Siena, Italy

  https://orcid.org/0000-0002-0170-1285

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• Maria Grazia Aruta,

  Roles Data curation, Investigation, Methodology, Writing – review & editing

  Affiliation GSK Vaccines Institute for Global Health S.r.l. (GVGH), Siena, Italy

  https://orcid.org/0000-0002-9248-9362

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• Gianmarco Gasperini,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation GSK Vaccines Institute for Global Health S.r.l. (GVGH), Siena, Italy

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• Renzo Alfini,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliation GSK Vaccines Institute for Global Health S.r.l. (GVGH), Siena, Italy

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• Simona Rondini,

  Roles Data curation, Methodology, Supervision, Writing – review & editing

  Affiliation GSK, Siena, Italy

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• Francesca Micoli,

  Roles Investigation, Supervision, Writing – review & editing

  Affiliation GSK Vaccines Institute for Global Health S.r.l. (GVGH), Siena, Italy

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• Rino Rappuoli,

  Roles Conceptualization, Writing – original draft, Writing – review & editing

  Affiliation GSK, Siena, Italy

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• Allan Saul ,

  Roles Conceptualization, Data curation, Formal analysis, Resources, Writing – original draft, Writing – review & editing

  ¶‡ Senior authors contributed equally to this work.

  Affiliation GSK Vaccines Institute for Global Health S.r.l. (GVGH), Siena, Italy

  https://orcid.org/0000-0003-0665-4091

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• Laura B. Martin

  Roles Conceptualization, Data curation, Formal analysis, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  ¶‡ Senior authors contributed equally to this work.

  Affiliation GSK Vaccines Institute for Global Health S.r.l. (GVGH), Siena, Italy

  https://orcid.org/0000-0001-7146-1283

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