Longitudinal TprK profiling of in vivo and in vitro-propagated Treponema pallidum subsp. pallidum reveals accumulation of antigenic variants in absence of immune pressure

• Michelle J. Lin,

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington, United States of America

  https://orcid.org/0000-0002-6925-9948

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• Austin M. Haynes,

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Pathobiology Graduate Program, University of Washington, Seattle, Washington, United States of America

  https://orcid.org/0000-0001-9122-9211

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• Amin Addetia,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliations Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington, United States of America, Molecular and Cellular Biology Graduate Program, University of Washington, Seattle, Washington, United States of America

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• Nicole A. P. Lieberman,

  Roles Investigation, Methodology

  Affiliation Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington, United States of America

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• Quynh Phung,

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington, United States of America

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• Hong Xie,

  Roles Data curation, Investigation, Methodology

  Affiliation Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington, United States of America

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• Tien V. Nguyen,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington, United States of America

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• Barbara J. Molini,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Medicine, Division of Allergy and Infectious Diseases, University of Washington, Seattle, Washington, United States of America

  https://orcid.org/0000-0003-4296-867X

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• Sheila A. Lukehart,

  Roles Funding acquisition, Resources, Writing – review & editing

  Affiliations Department of Medicine, Division of Allergy and Infectious Diseases, University of Washington, Seattle, Washington, United States of America, Department of Global Health, University of Washington, Seattle, Washington, United States of America

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• Lorenzo Giacani,

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing

  Affiliation Department of Medicine, Division of Allergy and Infectious Diseases, University of Washington, Seattle, Washington, United States of America

  https://orcid.org/0000-0003-3889-7274

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• Alexander L. Greninger

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: agrening@uw.edu

  Affiliations Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington, United States of America, Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

  https://orcid.org/0000-0002-7443-0527

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