Optimizing the microscopic agglutination test (MAT) panel for the diagnosis of Leptospirosis in a low resource, hyper-endemic setting with varied microgeographic variation in reactivity

• Dinesha Jayasundara,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft

  Affiliations Leptospirosis Research Laboratory, Department of Community Medicine, Faculty of Medicine and Allied Sciences, Rajarata University of Sri Lanka, Saliyapura, Sri Lanka, Department of Microbiology, Faculty of Medicine and Allied Sciences, Rajarata University of Sri Lanka, Saliyapura, Sri Lanka

  https://orcid.org/0000-0002-5573-0268

  ⨯
• Chandika Gamage,

  Roles Methodology, Supervision, Writing – review & editing

  Affiliation Department of Microbiology, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka

  https://orcid.org/0000-0003-0974-5730

  ⨯
• Indika Senavirathna,

  Roles Formal analysis, Investigation, Methodology

  Affiliations Leptospirosis Research Laboratory, Department of Community Medicine, Faculty of Medicine and Allied Sciences, Rajarata University of Sri Lanka, Saliyapura, Sri Lanka, Department of Biochemistry, Faculty of Medicine and Allied Sciences, Rajarata University of Sri Lanka, Saliyapura, Sri Lanka

  ⨯
• Janith Warnasekara,

  Roles Data curation, Formal analysis, Writing – review & editing

  Affiliation Department of Community Medicine, Faculty of Medicine and Allied Sciences, Rajarata University of Sri Lanka, Saliyapura, Sri Lanka

  ⨯
• Michael A. Matthias,

  Roles Supervision, Writing – review & editing

  Affiliation School of Medicine, Yale University, New Haven, Connecticut, United States of America

  ⨯
• Joseph M. Vinetz ,

  Roles Conceptualization, Funding acquisition, Methodology, Supervision, Writing – review & editing

  * E-mail: joseph.vinetz@yale.edu (JV); suneth.agampodi@yale.edu (SA)

  ¶‡ These authors are joint senior authors on this work.

  Affiliation School of Medicine, Yale University, New Haven, Connecticut, United States of America

  https://orcid.org/0000-0001-8344-2004

  ⨯
• Suneth Agampodi

  Roles Conceptualization, Data curation, Funding acquisition, Methodology, Project administration, Supervision, Writing – review & editing

  * E-mail: joseph.vinetz@yale.edu (JV); suneth.agampodi@yale.edu (SA)

  ¶‡ These authors are joint senior authors on this work.

  Affiliations Leptospirosis Research Laboratory, Department of Community Medicine, Faculty of Medicine and Allied Sciences, Rajarata University of Sri Lanka, Saliyapura, Sri Lanka, School of Medicine, Yale University, New Haven, Connecticut, United States of America

  https://orcid.org/0000-0001-7810-1774

  ⨯