An inactivated recombinant rabies virus displaying the Zika virus prM-E induces protective immunity against both pathogens

Hongli Jin; Cuicui Jiao; Zengguo Cao; Pei Huang; Hang Chi; Yujie Bai; Di Liu; Jianzhong Wang; Na Feng; Nan Li; Yongkun Zhao; Tiecheng Wang; Yuwei Gao; Songtao Yang; Xianzhu Xia; Hualei Wang

doi:10.1371/journal.pntd.0009484

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Open Access

Peer-reviewed

Research Article

An inactivated recombinant rabies virus displaying the Zika virus prM-E induces protective immunity against both pathogens

Hongli Jin,

Roles Conceptualization, Data curation, Methodology, Software, Writing – original draft, Writing – review & editing

Affiliations Key Laboratory of Zoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China, Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Institute of Military Veterinary, Academy of Military Medical Sciences, Changchun, China
⨯
Cuicui Jiao,

Roles Data curation, Methodology

Affiliation Key Laboratory of Zoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China
⨯
Zengguo Cao,

Roles Methodology

Affiliations Key Laboratory of Zoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China, Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Institute of Military Veterinary, Academy of Military Medical Sciences, Changchun, China
⨯
Pei Huang,

Roles Investigation, Methodology

Affiliations Key Laboratory of Zoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China, Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Institute of Military Veterinary, Academy of Military Medical Sciences, Changchun, China, College of Veterinary Medicine, Jilin Agricultural University, Changchun, China
⨯
Hang Chi,

Roles Investigation, Validation

Affiliation Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Institute of Military Veterinary, Academy of Military Medical Sciences, Changchun, China
⨯
Yujie Bai,

Roles Validation

Affiliation Key Laboratory of Zoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China
⨯
Di Liu,

Roles Formal analysis

Affiliations Key Laboratory of Zoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China, College of Veterinary Medicine, Jilin Agricultural University, Changchun, China
⨯
Jianzhong Wang,

Roles Formal analysis

Affiliation College of Veterinary Medicine, Jilin Agricultural University, Changchun, China
⨯
Na Feng,

Roles Data curation, Resources

Affiliation Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Institute of Military Veterinary, Academy of Military Medical Sciences, Changchun, China
⨯
Nan Li,

Roles Resources, Software

Affiliation Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Institute of Military Veterinary, Academy of Military Medical Sciences, Changchun, China
⨯
Yongkun Zhao,

Roles Resources, Visualization

Affiliation Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Institute of Military Veterinary, Academy of Military Medical Sciences, Changchun, China
⨯
Tiecheng Wang,

Roles Resources, Visualization

Affiliation Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Institute of Military Veterinary, Academy of Military Medical Sciences, Changchun, China
⨯
Yuwei Gao,

Roles Resources, Supervision

Affiliation Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Institute of Military Veterinary, Academy of Military Medical Sciences, Changchun, China
⨯
Songtao Yang,

Roles Supervision, Writing – review & editing

Affiliation Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Institute of Military Veterinary, Academy of Military Medical Sciences, Changchun, China
⨯
Xianzhu Xia ,

Roles Conceptualization, Project administration

* E-mail: xiaxzh@cae.cn (XX); wanghualei@jlu.edu.cn (HW)

Affiliations Key Laboratory of Zoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China, Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Institute of Military Veterinary, Academy of Military Medical Sciences, Changchun, China
⨯
[ ... ],
Hualei Wang

Roles Conceptualization, Funding acquisition, Project administration, Writing – review & editing

* E-mail: xiaxzh@cae.cn (XX); wanghualei@jlu.edu.cn (HW)

Affiliations Key Laboratory of Zoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China, Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Institute of Military Veterinary, Academy of Military Medical Sciences, Changchun, China

https://orcid.org/0000-0001-6961-1991

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An inactivated recombinant rabies virus displaying the Zika virus prM-E induces protective immunity against both pathogens

Hongli Jin,
Cuicui Jiao,
Zengguo Cao,
Pei Huang,
Hang Chi,
Yujie Bai,
Di Liu,
Jianzhong Wang,
Na Feng,
Nan Li

Published: June 4, 2021
https://doi.org/10.1371/journal.pntd.0009484

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