A novel mechanism of streptomycin resistance in Yersinia pestis: Mutation in the rpsL gene

Ruixia Dai; Jian He; Xi Zha; Yiting Wang; Xuefei Zhang; He Gao; Xiaoyan Yang; Juan Li; Youquan Xin; Yumeng Wang; Sheng Li; Juan Jin; Qi Zhang; Jixiang Bai; Yao Peng; Hailian Wu; Qingwen Zhang; Baiqing Wei; Jianguo Xu; Wei Li

doi:10.1371/journal.pntd.0009324

Loading metrics

Open Access

Peer-reviewed

Research Article

A novel mechanism of streptomycin resistance in Yersinia pestis: Mutation in the rpsL gene

Ruixia Dai ,

Contributed equally to this work with: Ruixia Dai, Jian He, Xi Zha, Yiting Wang, Xuefei Zhang

Roles Conceptualization, Funding acquisition, Investigation, Project administration, Supervision, Writing – original draft

Affiliations Qinghai Institute for Endemic Disease Control and Prevention, Xining, China, Key Laboratory of the National Health Commission for Plague Control and Prevention, Xining, China
⨯
Jian He ,

Contributed equally to this work with: Ruixia Dai, Jian He, Xi Zha, Yiting Wang, Xuefei Zhang

Roles Data curation, Formal analysis, Investigation, Methodology, Visualization

Affiliations Qinghai Institute for Endemic Disease Control and Prevention, Xining, China, Key Laboratory of the National Health Commission for Plague Control and Prevention, Xining, China
⨯
Xi Zha ,

Contributed equally to this work with: Ruixia Dai, Jian He, Xi Zha, Yiting Wang, Xuefei Zhang

Roles Investigation, Resources, Validation, Writing – original draft

Affiliation Center for Disease Control and Prevention of Tibet Autonomous Region, Lhasa, China
⨯
Yiting Wang ,

Contributed equally to this work with: Ruixia Dai, Jian He, Xi Zha, Yiting Wang, Xuefei Zhang

Roles Data curation, Formal analysis, Software, Visualization

Affiliations National Institute for Communicable Disease Control and Prevention, China CDC, Changping, Beijing, China, State Key Laboratory of Infectious Disease Prevention and Control, Beijing, China
⨯
Xuefei Zhang ,

Contributed equally to this work with: Ruixia Dai, Jian He, Xi Zha, Yiting Wang, Xuefei Zhang

Roles Conceptualization, Funding acquisition, Resources

Affiliations Qinghai Institute for Endemic Disease Control and Prevention, Xining, China, Key Laboratory of the National Health Commission for Plague Control and Prevention, Xining, China
⨯
He Gao,

Roles Methodology

Affiliations National Institute for Communicable Disease Control and Prevention, China CDC, Changping, Beijing, China, State Key Laboratory of Infectious Disease Prevention and Control, Beijing, China
⨯
Xiaoyan Yang,

Roles Investigation

Affiliations Qinghai Institute for Endemic Disease Control and Prevention, Xining, China, Key Laboratory of the National Health Commission for Plague Control and Prevention, Xining, China
⨯
Juan Li,

Roles Methodology, Resources

Affiliations National Institute for Communicable Disease Control and Prevention, China CDC, Changping, Beijing, China, State Key Laboratory of Infectious Disease Prevention and Control, Beijing, China
⨯
Youquan Xin,

Roles Data curation, Investigation

Affiliations Qinghai Institute for Endemic Disease Control and Prevention, Xining, China, Key Laboratory of the National Health Commission for Plague Control and Prevention, Xining, China
⨯
Yumeng Wang,

Roles Visualization

Affiliations National Institute for Communicable Disease Control and Prevention, China CDC, Changping, Beijing, China, State Key Laboratory of Infectious Disease Prevention and Control, Beijing, China

https://orcid.org/0000-0002-2651-665X

⨯
Sheng Li,

Roles Investigation

Affiliations Qinghai Institute for Endemic Disease Control and Prevention, Xining, China, Key Laboratory of the National Health Commission for Plague Control and Prevention, Xining, China
⨯
Juan Jin,

Roles Data curation, Investigation

Affiliations Qinghai Institute for Endemic Disease Control and Prevention, Xining, China, Key Laboratory of the National Health Commission for Plague Control and Prevention, Xining, China
⨯
Qi Zhang,

Roles Investigation

Affiliations Qinghai Institute for Endemic Disease Control and Prevention, Xining, China, Key Laboratory of the National Health Commission for Plague Control and Prevention, Xining, China
⨯
Jixiang Bai,

Roles Data curation, Investigation

Affiliations Qinghai Institute for Endemic Disease Control and Prevention, Xining, China, Key Laboratory of the National Health Commission for Plague Control and Prevention, Xining, China
⨯
Yao Peng,

Roles Investigation

Affiliations National Institute for Communicable Disease Control and Prevention, China CDC, Changping, Beijing, China, State Key Laboratory of Infectious Disease Prevention and Control, Beijing, China
⨯
Hailian Wu,

Roles Resources

Affiliations Qinghai Institute for Endemic Disease Control and Prevention, Xining, China, Key Laboratory of the National Health Commission for Plague Control and Prevention, Xining, China
⨯
Qingwen Zhang,

Roles Resources

Affiliations Qinghai Institute for Endemic Disease Control and Prevention, Xining, China, Key Laboratory of the National Health Commission for Plague Control and Prevention, Xining, China
⨯
Baiqing Wei,

Roles Investigation, Validation

Affiliations Qinghai Institute for Endemic Disease Control and Prevention, Xining, China, Key Laboratory of the National Health Commission for Plague Control and Prevention, Xining, China
⨯
Jianguo Xu,

Roles Conceptualization, Supervision

Affiliations National Institute for Communicable Disease Control and Prevention, China CDC, Changping, Beijing, China, State Key Laboratory of Infectious Disease Prevention and Control, Beijing, China
⨯
[ ... ],
Wei Li

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

* E-mail: liwei@icdc.cn

Affiliations National Institute for Communicable Disease Control and Prevention, China CDC, Changping, Beijing, China, State Key Laboratory of Infectious Disease Prevention and Control, Beijing, China

https://orcid.org/0000-0002-3257-1540

⨯
[ view all ]
[ view less ]

A novel mechanism of streptomycin resistance in Yersinia pestis: Mutation in the rpsL gene

Ruixia Dai,
Jian He,
Xi Zha,
Yiting Wang,
Xuefei Zhang,
He Gao,
Xiaoyan Yang,
Juan Li,
Youquan Xin,
Yumeng Wang

Published: April 22, 2021
https://doi.org/10.1371/journal.pntd.0009324

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Streptomycin
Is the Subject Area "Streptomycin" applicable to this article?

Thanks for your feedback.
Plagues
Is the Subject Area "Plagues" applicable to this article?

Thanks for your feedback.
Substitution mutation
Is the Subject Area "Substitution mutation" applicable to this article?

Thanks for your feedback.
Antibiotic resistance
Is the Subject Area "Antibiotic resistance" applicable to this article?

Thanks for your feedback.
Mutation
Is the Subject Area "Mutation" applicable to this article?

Thanks for your feedback.
Plasmids
Is the Subject Area "Plasmids" applicable to this article?

Thanks for your feedback.
Pneumonic plagues
Is the Subject Area "Pneumonic plagues" applicable to this article?

Thanks for your feedback.
Mycobacterium tuberculosis
Is the Subject Area "Mycobacterium tuberculosis" applicable to this article?

Thanks for your feedback.