Extracellular vesicles secreted by Giardia duodenalis regulate host cell innate immunity via TLR2 and NLRP3 inflammasome signaling pathways

• Panpan Zhao ,

  Contributed equally to this work with: Panpan Zhao, Lili Cao, Xiaocen Wang

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Writing – original draft

  Affiliations Key Laboratory of Zoonosis, College of Veterinary Medicine, Jilin University, Changchun, China, Jiangsu Key Laboratory of Marine Biological Resources and Environment, Jiangsu Key Laboratory of Marine Pharmaceutical Compound Screening, Co-Innovation Center of Jiangsu Marine Bio-industry Technology, Jiangsu Ocean University, Lianyungang, China

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• Lili Cao ,

  Contributed equally to this work with: Panpan Zhao, Lili Cao, Xiaocen Wang

  Roles Conceptualization, Formal analysis, Investigation, Methodology

  Affiliations Key Laboratory of Zoonosis, College of Veterinary Medicine, Jilin University, Changchun, China, Jilin Academy of Animal Husbandry and Veterinary Medicine, Changchun, China

  https://orcid.org/0000-0001-7583-2221

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• Xiaocen Wang ,

  Contributed equally to this work with: Panpan Zhao, Lili Cao, Xiaocen Wang

  Roles Conceptualization, Formal analysis, Methodology

  Affiliation Key Laboratory of Zoonosis, College of Veterinary Medicine, Jilin University, Changchun, China

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• Jingquan Dong,

  Roles Data curation, Formal analysis, Methodology, Validation

  Affiliation Jiangsu Key Laboratory of Marine Biological Resources and Environment, Jiangsu Key Laboratory of Marine Pharmaceutical Compound Screening, Co-Innovation Center of Jiangsu Marine Bio-industry Technology, Jiangsu Ocean University, Lianyungang, China

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• Nan Zhang,

  Roles Methodology, Supervision, Validation, Visualization

  Affiliation Key Laboratory of Zoonosis, College of Veterinary Medicine, Jilin University, Changchun, China

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• Xin Li,

  Roles Formal analysis, Methodology, Resources, Visualization

  Affiliation Key Laboratory of Zoonosis, College of Veterinary Medicine, Jilin University, Changchun, China

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• Jianhua Li,

  Roles Resources, Supervision, Validation, Visualization

  Affiliation Key Laboratory of Zoonosis, College of Veterinary Medicine, Jilin University, Changchun, China

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• Xichen Zhang,

  Roles Conceptualization, Formal analysis, Project administration, Resources, Visualization

  Affiliation Key Laboratory of Zoonosis, College of Veterinary Medicine, Jilin University, Changchun, China

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• Pengtao Gong

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Validation, Writing – review & editing

  * E-mail: gongpt@jlu.edu.cn

  Affiliation Key Laboratory of Zoonosis, College of Veterinary Medicine, Jilin University, Changchun, China

  https://orcid.org/0000-0001-9696-9681

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