A systematic review and an individual patient data meta-analysis of ivermectin use in children weighing less than fifteen kilograms: Is it time to reconsider the current contraindication?

• Podjanee Jittamala ,

  Contributed equally to this work with: Podjanee Jittamala, Wuelton Monteiro

  Roles Conceptualization, Formal analysis, Writing – original draft

  Affiliations Department of Tropical Hygiene, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

  https://orcid.org/0000-0002-1020-2760

  ⨯
• Wuelton Monteiro ,

  Contributed equally to this work with: Podjanee Jittamala, Wuelton Monteiro

  Roles Conceptualization, Formal analysis, Writing – original draft

  Affiliations Fundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, Brazil, Universidade do Estado do Amazonas, Manaus, Brazil

  ⨯
• Menno R. Smit,

  Roles Writing – original draft

  Affiliations Amsterdam Centre for Global Child Health, Emma Children’s Hospital, Amsterdam, The Netherlands, University Medical Centres, University of Amsterdam, Amsterdam, The Netherlands, Malaria Epidemiology Unit, Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom

  https://orcid.org/0000-0003-3405-6638

  ⨯
• Belen Pedrique,

  Roles Writing – original draft

  Affiliation Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland

  ⨯
• Sabine Specht,

  Roles Writing – original draft

  Affiliation Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland

  ⨯
• Carlos J. Chaccour,

  Roles Investigation, Writing – original draft

  Affiliations ISGlobal, Hospital Clínic—Universitat de Barcelona, Barcelona, Spain, Centro de Investigação em Saúde de Manhiça, Maputo, Mozambique, Ifakara Health Institute, Ifakara, United Republic of Tanzania, Instituto de Medicina Tropical Universidad de Navarra, Pamplona, Spain

  https://orcid.org/0000-0001-9812-050X

  ⨯
• Céline Dard,

  Roles Investigation, Writing – review & editing

  Affiliation Laboratoire de Biologie Médicale, Centre Hospitalier de Basse-Terre, Basse-Terre, Guadeloupe, France

  https://orcid.org/0000-0002-5843-0842

  ⨯
• Pascal Del Giudice,

  Roles Investigation, Writing – review & editing

  Affiliation Infectious Diseases and Dermatology Unit, Hospital of Fréjus-Saint-Raphaël, Fréjus, France

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• Virak Khieu,

  Roles Investigation, Writing – review & editing

  Affiliation National Centre for Parasitology, Entomology and Malaria Control, Ministry of Health, Phnom Penh, Cambodia

  ⨯
• Annabel Maruani,

  Roles Investigation, Writing – review & editing

  Affiliation Unit of Pediatric Dermatology, University Hospital Center of Tours, University of Tours, Tours, France

  https://orcid.org/0000-0003-3734-810X

  ⨯
• Virgilio E. Failoc-Rojas,

  Roles Investigation, Writing – original draft

  Affiliations Unidad de investigacion para la generacion y sintesis de evidencias en salud, Universidad San Ignacio de Loyola, Lima, Peru, Laboratorio de Parasitologia, Metaxenicas y Zoonosis, Hospital Regional Lambayeque, Lambayeque, Peru

  https://orcid.org/0000-0003-2992-9342

  ⨯
• Marimar Sáez-de-Ocariz,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Dermatology, National Institute of Pediatrics, Mexico City, Mexico

  https://orcid.org/0000-0003-4726-2983

  ⨯
• Antoni Soriano-Arandes,

  Roles Investigation, Writing – review & editing

  Affiliation Pediatric Infectious Diseases and Immunodeficiencies Unit, Hospital Universitari Vall d’Hebron, Vall d’Hebron Research Institute, Barcelona, Spain

  https://orcid.org/0000-0001-9613-7228

  ⨯
• Jaime Piquero-Casals,

  Roles Investigation, Writing – review & editing

  Affiliation Dermik, Multidisciplinary Dermatology Clinic, Barcelona, Spain

  https://orcid.org/0000-0002-4481-5602

  ⨯
• Anne Faisant,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Pediatrics, University Hospital Grenoble-Alpes, Grenoble, France

  ⨯
• Marie-Pierre Brenier-Pinchart,

  Roles Investigation, Writing – review & editing

  Affiliation Departement of Parasitology-Mycology, University Hospital Grenoble-Alpes, Grenoble, France

  https://orcid.org/0000-0003-1366-5856

  ⨯
• David Wimmersberger,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, University of Basel, Basel, Switzerland

  https://orcid.org/0000-0001-7557-4197

  ⨯
• Jean T. Coulibaly,

  Roles Investigation, Writing – review & editing

  Affiliations Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, University of Basel, Basel, Switzerland, Unité de Formation et de Recherche Biosciences, Université Félix Houphouët-Boigny, Abidjan, Côte d’Ivoire, Centre Suisse de Recherches Scientifiques en Côte d’Ivoire, Abidjan, Côte d’Ivoire

  ⨯
• Jennifer Keiser,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, University of Basel, Basel, Switzerland

  https://orcid.org/0000-0003-0290-3521

  ⨯
• Franck Boralevi,

  Roles Investigation, Writing – review & editing

  Affiliations Paediatric Dermatology Unit, Children hospital, Bordeaux University Hospital, Bordeaux, France, Centre d’investigation clinique pédiatrique 1401 module plurithématique, Bordeaux University, Bordeaux, France

  ⨯
• Oliver Sokana ,

  Roles Investigation, Writing – review & editing

  ¶‡ Unavailable.

  Affiliation Ministry of Health and Medical Services, Honiara, Solomon Islands

  ⨯
• Michael Marks,

  Roles Investigation, Writing – review & editing

  Affiliations Clinical Research Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom, Hospital for Tropical Diseases, London, United Kingdom

  https://orcid.org/0000-0002-7585-4743

  ⨯
• Daniel Engelman,

  Roles Investigation, Writing – review & editing

  Affiliations Tropical Diseases, Murdoch Children’s Research Institute, Melbourne, VIC, Australia, Department of Paediatrics, University of Melbourne, Melbourne, VIC, Australia

  https://orcid.org/0000-0002-4909-1287

  ⨯
• Lucia Romani,

  Roles Investigation, Writing – review & editing

  Affiliations Tropical Diseases, Murdoch Children’s Research Institute, Melbourne, VIC, Australia, The Kirby Institute, UNSW, Sydney, NSW, Australia

  https://orcid.org/0000-0001-9038-5300

  ⨯
• Andrew C. Steer,

  Roles Investigation, Writing – original draft

  Affiliations Tropical Diseases, Murdoch Children’s Research Institute, Melbourne, VIC, Australia, Department of Paediatrics, University of Melbourne, Melbourne, VIC, Australia

  https://orcid.org/0000-0001-7346-0196

  ⨯
• Lorenz von Seidlein,

  Roles Writing – original draft

  Affiliations Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand, Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, United Kingdom

  https://orcid.org/0000-0002-0282-6469

  ⨯
• Nicholas J. White,

  Roles Conceptualization, Writing – review & editing

  Affiliations Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand, Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, United Kingdom

  https://orcid.org/0000-0002-1897-1978

  ⨯
• Eli Harriss,

  Roles Formal analysis, Writing – review & editing

  Affiliation The Knowledge Centre, Bodleian Health Care Libraries, University of Oxford, Oxford, United Kingdom

  https://orcid.org/0000-0003-4635-8959

  ⨯
• Kasia Stepniewska,

  Roles Formal analysis, Methodology, Writing – original draft

  Affiliations Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, United Kingdom, WorldWide Antimalarial Resistance Network (WWARN), Oxford, United Kingdom

  https://orcid.org/0000-0002-1713-6209

  ⨯
• Georgina S. Humphreys,

  Roles Data curation, Methodology, Writing – review & editing

  Affiliations WorldWide Antimalarial Resistance Network (WWARN), Oxford, United Kingdom, Green Templeton College, University of Oxford, United Kingdom

  https://orcid.org/0000-0001-9947-0034

  ⨯
• Kalynn Kennon,

  Roles Data curation, Writing – review & editing

  Affiliations Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, United Kingdom, WorldWide Antimalarial Resistance Network (WWARN), Oxford, United Kingdom

  https://orcid.org/0000-0003-3531-0298

  ⨯
• Philippe J. Guerin,

  Roles Conceptualization, Methodology, Project administration, Writing – review & editing

  Affiliations Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, United Kingdom, WorldWide Antimalarial Resistance Network (WWARN), Oxford, United Kingdom, Infectious Diseases Data Observatory (IDDO), Oxford, United Kingdom

  https://orcid.org/0000-0002-6008-2963

  ⨯
•  [ ... ],
• Kevin C. Kobylinski

  Roles Conceptualization, Formal analysis, Methodology, Writing – original draft, Writing – review & editing

  * E-mail: kobylinskikevin@yahoo.com

  Affiliation Department of Entomology, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand

  https://orcid.org/0000-0002-4807-9681

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