Polymorphisms in mitochondrial ribosomal protein S5 (MRPS5) are associated with leprosy risk in Chinese

Yan Xing; Jun He; Yan Wen; Jian Liu; Yuangang You; Xiaoman Weng; Lianchao Yuan; Li Xiong; Xiaohua Chen; Ying Zhang; Huan-Ying Li

doi:10.1371/journal.pntd.0008883

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Open Access

Peer-reviewed

Research Article

Polymorphisms in mitochondrial ribosomal protein S5 (MRPS5) are associated with leprosy risk in Chinese

Yan Xing,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliations Beijing Tropical Medicine Research Institute, Beijing Friendship Hospital, Capital Medical University, Beijing, China, Beijing Key Laboratory for Research on Prevention and Treatment of Tropical Diseases, Beijing, China

https://orcid.org/0000-0001-5355-5067

⨯
Jun He,

Roles Data curation, Investigation, Methodology, Resources

Affiliation Leprosy Research Center, Yunnan Center for Disease Control and Prevention, Kunming, China
⨯
Yan Wen,

Roles Data curation, Investigation, Methodology, Resources

Affiliations Beijing Tropical Medicine Research Institute, Beijing Friendship Hospital, Capital Medical University, Beijing, China, Beijing Key Laboratory for Research on Prevention and Treatment of Tropical Diseases, Beijing, China
⨯
Jian Liu,

Roles Data curation, Investigation, Methodology, Resources

Affiliations Beijing Tropical Medicine Research Institute, Beijing Friendship Hospital, Capital Medical University, Beijing, China, Beijing Key Laboratory for Research on Prevention and Treatment of Tropical Diseases, Beijing, China
⨯
Yuangang You,

Roles Data curation, Investigation, Methodology, Resources

Affiliations Beijing Tropical Medicine Research Institute, Beijing Friendship Hospital, Capital Medical University, Beijing, China, Beijing Key Laboratory for Research on Prevention and Treatment of Tropical Diseases, Beijing, China
⨯
Xiaoman Weng,

Roles Conceptualization, Data curation, Resources

Affiliations Beijing Tropical Medicine Research Institute, Beijing Friendship Hospital, Capital Medical University, Beijing, China, Beijing Key Laboratory for Research on Prevention and Treatment of Tropical Diseases, Beijing, China
⨯
Lianchao Yuan,

Roles Data curation, Resources

Affiliations Beijing Tropical Medicine Research Institute, Beijing Friendship Hospital, Capital Medical University, Beijing, China, Beijing Key Laboratory for Research on Prevention and Treatment of Tropical Diseases, Beijing, China
⨯
Li Xiong,

Roles Data curation, Resources

Affiliation Leprosy Research Center, Yunnan Center for Disease Control and Prevention, Kunming, China
⨯
Xiaohua Chen,

Roles Data curation

Affiliations Beijing Tropical Medicine Research Institute, Beijing Friendship Hospital, Capital Medical University, Beijing, China, Beijing Key Laboratory for Research on Prevention and Treatment of Tropical Diseases, Beijing, China
⨯
Ying Zhang ,

Roles Conceptualization, Project administration, Writing – review & editing

* E-mail: yz207913@163.com (YZ); lihybj@163.com (H-YL)

Affiliation State Key Laboratory for the Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
⨯
Huan-Ying Li

Roles Conceptualization, Funding acquisition, Project administration, Writing – review & editing

* E-mail: yz207913@163.com (YZ); lihybj@163.com (H-YL)

Affiliations Beijing Tropical Medicine Research Institute, Beijing Friendship Hospital, Capital Medical University, Beijing, China, Beijing Key Laboratory for Research on Prevention and Treatment of Tropical Diseases, Beijing, China

https://orcid.org/0000-0002-8924-3839

⨯

Polymorphisms in mitochondrial ribosomal protein S5 (MRPS5) are associated with leprosy risk in Chinese

Yan Xing,
Jun He,
Yan Wen,
Jian Liu,
Yuangang You,
Xiaoman Weng,
Lianchao Yuan,
Li Xiong,
Xiaohua Chen,
Ying Zhang

Published: December 23, 2020
https://doi.org/10.1371/journal.pntd.0008883

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Leprosy
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Mycobacterium leprae
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Medical risk factors
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Single nucleotide polymorphisms
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Dideoxy DNA sequencing
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Genotyping
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Genetic loci
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