Immunoreactivity and neutralization study of Chinese Bungarus multicinctus antivenin and lab-prepared anti-bungarotoxin antisera towards purified bungarotoxins and snake venoms

• Bo Lin ,

  Contributed equally to this work with: Bo Lin, Jia-Rui Zhang

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliations College of Life Sciences, Anhui Normal University, Wuhu, Anhui, China, Key Laboratory of Animal Models and Human Disease Mechanisms of The Chinese Academy of Sciences/Key Laboratory of Bioactive Peptides of Yunnan Province, Kunming Institute of Zoology, the Chinese Academy of Sciences, Kunming, Yunnan, China

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• Jia-Rui Zhang ,

  Contributed equally to this work with: Bo Lin, Jia-Rui Zhang

  Roles Data curation, Formal analysis, Investigation, Methodology

  Affiliation Nanshan School, Guangzhou Medical University, Guangzhou, Guandong, China

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• Hui-Juan Lu,

  Roles Data curation, Formal analysis, Investigation

  Affiliation Key Laboratory of Animal Models and Human Disease Mechanisms of The Chinese Academy of Sciences/Key Laboratory of Bioactive Peptides of Yunnan Province, Kunming Institute of Zoology, the Chinese Academy of Sciences, Kunming, Yunnan, China

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• Lin Zhao,

  Roles Data curation, Formal analysis

  Affiliations College of Life Sciences, Anhui Normal University, Wuhu, Anhui, China, Key Laboratory of Animal Models and Human Disease Mechanisms of The Chinese Academy of Sciences/Key Laboratory of Bioactive Peptides of Yunnan Province, Kunming Institute of Zoology, the Chinese Academy of Sciences, Kunming, Yunnan, China

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• Jing Chen,

  Roles Data curation, Formal analysis

  Affiliations Key Laboratory of Animal Models and Human Disease Mechanisms of The Chinese Academy of Sciences/Key Laboratory of Bioactive Peptides of Yunnan Province, Kunming Institute of Zoology, the Chinese Academy of Sciences, Kunming, Yunnan, China, School of Life and Pharmaceutical Sciences, Hainan University, Haikou, Hainan, China

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• Hong-Fei Zhang,

  Roles Data curation, Formal analysis

  Affiliation Key Laboratory of Animal Models and Human Disease Mechanisms of The Chinese Academy of Sciences/Key Laboratory of Bioactive Peptides of Yunnan Province, Kunming Institute of Zoology, the Chinese Academy of Sciences, Kunming, Yunnan, China

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• Xue-Song Wei,

  Roles Data curation, Formal analysis

  Affiliations College of Life Sciences, Anhui Normal University, Wuhu, Anhui, China, Key Laboratory of Animal Models and Human Disease Mechanisms of The Chinese Academy of Sciences/Key Laboratory of Bioactive Peptides of Yunnan Province, Kunming Institute of Zoology, the Chinese Academy of Sciences, Kunming, Yunnan, China

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• Liang-Yu Zhang,

  Roles Data curation, Formal analysis

  Affiliation Key Laboratory of Animal Models and Human Disease Mechanisms of The Chinese Academy of Sciences/Key Laboratory of Bioactive Peptides of Yunnan Province, Kunming Institute of Zoology, the Chinese Academy of Sciences, Kunming, Yunnan, China

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• Xiao-Bing Wu ,

  Roles Conceptualization, Methodology

  * E-mail: wuxb@mail.ahnu.edu.cn (XBW); leewh@mail.kiz.ac.cn (WHL)

  Affiliation College of Life Sciences, Anhui Normal University, Wuhu, Anhui, China

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• Wen-Hui Lee

  Roles Conceptualization, Funding acquisition, Investigation, Resources, Supervision, Writing – review & editing

  * E-mail: wuxb@mail.ahnu.edu.cn (XBW); leewh@mail.kiz.ac.cn (WHL)

  Affiliation Key Laboratory of Animal Models and Human Disease Mechanisms of The Chinese Academy of Sciences/Key Laboratory of Bioactive Peptides of Yunnan Province, Kunming Institute of Zoology, the Chinese Academy of Sciences, Kunming, Yunnan, China

  https://orcid.org/0000-0003-2621-5782

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