Recombinant CsHscB of carcinogenic liver fluke Clonorchis sinensis induces IL-10 production by binding with TLR2

• Chao Yan ,

  Contributed equally to this work with: Chao Yan, Fan Fang

  Roles Data curation, Funding acquisition, Investigation, Writing – original draft

  Affiliations Jiangsu Key Laboratory of Immunity and Metabolism, Department of Pathogenic Biology and Immunology, Laboratory of Infection and Immunity, Xuzhou Medical University, Xuzhou, P. R. China, National Experimental Demonstration Center for Basic Medicine Education, Department of Clinical Medicine, Xuzhou Medical University, Xuzhou, P. R. China

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• Fan Fang ,

  Contributed equally to this work with: Chao Yan, Fan Fang

  Roles Data curation, Formal analysis, Investigation, Validation

  Affiliation Jiangsu Key Laboratory of Immunity and Metabolism, Department of Pathogenic Biology and Immunology, Laboratory of Infection and Immunity, Xuzhou Medical University, Xuzhou, P. R. China

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• Yu-Zhao Zhang,

  Roles Methodology

  Affiliation Jiangsu Key Laboratory of Immunity and Metabolism, Department of Pathogenic Biology and Immunology, Laboratory of Infection and Immunity, Xuzhou Medical University, Xuzhou, P. R. China

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• Xin Dong,

  Roles Methodology

  Affiliation Jiangsu Key Laboratory of Immunity and Metabolism, Department of Pathogenic Biology and Immunology, Laboratory of Infection and Immunity, Xuzhou Medical University, Xuzhou, P. R. China

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• Jing Wu,

  Roles Methodology

  Affiliation Jiangsu Key Laboratory of Immunity and Metabolism, Department of Pathogenic Biology and Immunology, Laboratory of Infection and Immunity, Xuzhou Medical University, Xuzhou, P. R. China

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• Hai-Liang Liu,

  Roles Methodology

  Affiliation CapitalBio Technology Inc., Beijing, P.R. China

  http://orcid.org/0000-0002-4364-2826

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• Chun-Yang Fan,

  Roles Methodology

  Affiliations Jiangsu Key Laboratory of Immunity and Metabolism, Department of Pathogenic Biology and Immunology, Laboratory of Infection and Immunity, Xuzhou Medical University, Xuzhou, P. R. China, National Experimental Demonstration Center for Basic Medicine Education, Department of Clinical Medicine, Xuzhou Medical University, Xuzhou, P. R. China

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• Stephane Koda,

  Roles Writing – review & editing

  Affiliation Jiangsu Key Laboratory of Immunity and Metabolism, Department of Pathogenic Biology and Immunology, Laboratory of Infection and Immunity, Xuzhou Medical University, Xuzhou, P. R. China

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• Bei-Bei Zhang,

  Roles Methodology

  Affiliations Jiangsu Key Laboratory of Immunity and Metabolism, Department of Pathogenic Biology and Immunology, Laboratory of Infection and Immunity, Xuzhou Medical University, Xuzhou, P. R. China, National Experimental Demonstration Center for Basic Medicine Education, Department of Clinical Medicine, Xuzhou Medical University, Xuzhou, P. R. China

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• Qian Yu,

  Roles Funding acquisition, Investigation, Methodology

  Affiliations Jiangsu Key Laboratory of Immunity and Metabolism, Department of Pathogenic Biology and Immunology, Laboratory of Infection and Immunity, Xuzhou Medical University, Xuzhou, P. R. China, National Experimental Demonstration Center for Basic Medicine Education, Department of Clinical Medicine, Xuzhou Medical University, Xuzhou, P. R. China

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• Liang Wang,

  Roles Methodology

  Affiliation College of Bioinformatics, Xuzhou Medical University, Xuzhou, P. R. China

  http://orcid.org/0000-0001-5339-7484

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• Yu-Gang Wang,

  Roles Methodology

  Affiliations Jiangsu Key Laboratory of Immunity and Metabolism, Department of Pathogenic Biology and Immunology, Laboratory of Infection and Immunity, Xuzhou Medical University, Xuzhou, P. R. China, National Experimental Demonstration Center for Basic Medicine Education, Department of Clinical Medicine, Xuzhou Medical University, Xuzhou, P. R. China

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• Jia-Xu Chen,

  Roles Methodology

  Affiliation National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Key Laboratory of Parasite and Vector Biology, Ministry of Health, WHO Collaborating Center of Malaria, Schistosomiasis, and Filariasis, Shanghai, P. R. China

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• Kui-Yang Zheng

  Roles Conceptualization, Funding acquisition, Supervision

  * E-mail: zky@xzhmu.edu.cn

  Affiliations Jiangsu Key Laboratory of Immunity and Metabolism, Department of Pathogenic Biology and Immunology, Laboratory of Infection and Immunity, Xuzhou Medical University, Xuzhou, P. R. China, National Experimental Demonstration Center for Basic Medicine Education, Department of Clinical Medicine, Xuzhou Medical University, Xuzhou, P. R. China

  http://orcid.org/0000-0002-1896-7485

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