Efficacy and safety of praziquantel and dihydroartemisinin piperaquine combination for treatment and control of intestinal schistosomiasis: A randomized, non-inferiority clinical trial

Rajabu Hussein Mnkugwe; Omary Minzi; Safari Kinung’hi; Appolinary Kamuhabwa; Eleni Aklillu

doi:10.1371/journal.pntd.0008619

Loading metrics

Open Access

Peer-reviewed

Research Article

Efficacy and safety of praziquantel and dihydroartemisinin piperaquine combination for treatment and control of intestinal schistosomiasis: A randomized, non-inferiority clinical trial

Rajabu Hussein Mnkugwe,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

Affiliations Department of Clinical Pharmacology, School of Medicine, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania, Division of Clinical Pharmacology, Department of Laboratory Medicine, Karolinska University Hospital-Huddinge, Karolinska Institutet, Stockholm, Sweden
⨯
Omary Minzi,

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – review & editing

Affiliation Department of Clinical Pharmacy and Pharmacology, School of Pharmacy, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania
⨯
Safari Kinung’hi,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Supervision, Writing – review & editing

Affiliation National Institute for Medical Research (NIMR), Mwanza Research Centre, Mwanza, Tanzania
⨯
Appolinary Kamuhabwa,

Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Supervision, Writing – review & editing

Affiliation Department of Clinical Pharmacy and Pharmacology, School of Pharmacy, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania
⨯
Eleni Aklillu

Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – review & editing

* E-mail: eleni.aklillu@ki.se

Affiliation Division of Clinical Pharmacology, Department of Laboratory Medicine, Karolinska University Hospital-Huddinge, Karolinska Institutet, Stockholm, Sweden

http://orcid.org/0000-0002-9788-0790

⨯

Efficacy and safety of praziquantel and dihydroartemisinin piperaquine combination for treatment and control of intestinal schistosomiasis: A randomized, non-inferiority clinical trial

Rajabu Hussein Mnkugwe,
Omary Minzi,
Safari Kinung’hi,
Appolinary Kamuhabwa,
Eleni Aklillu

Published: September 23, 2020
https://doi.org/10.1371/journal.pntd.0008619

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Schistosomiasis
Is the Subject Area "Schistosomiasis" applicable to this article?

Thanks for your feedback.
Adverse events
Is the Subject Area "Adverse events" applicable to this article?

Thanks for your feedback.
Eggs
Is the Subject Area "Eggs" applicable to this article?

Thanks for your feedback.
Intestinal schistosomiasis
Is the Subject Area "Intestinal schistosomiasis" applicable to this article?

Thanks for your feedback.
Parasitic diseases
Is the Subject Area "Parasitic diseases" applicable to this article?

Thanks for your feedback.
Drug therapy
Is the Subject Area "Drug therapy" applicable to this article?

Thanks for your feedback.
Malaria
Is the Subject Area "Malaria" applicable to this article?

Thanks for your feedback.
Drug administration
Is the Subject Area "Drug administration" applicable to this article?

Thanks for your feedback.