Click chemistry-facilitated comprehensive identification of proteins adducted by antimicrobial 5-nitroimidazoles for discovery of alternative drug targets against giardiasis

• Tineke Lauwaet,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Pathology, University of California, San Diego, La Jolla, California, United States of America

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• Yukiko Miyamoto,

  Roles Data curation, Investigation, Methodology, Writing – review & editing

  Affiliation Department of Medicine, University of California, San Diego, La Jolla, California, United States of America

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• Sozaburo Ihara,

  Roles Investigation, Validation, Writing – review & editing

  Affiliations Department of Medicine, University of California, San Diego, La Jolla, California, United States of America, Division of Gastroenterology, The Institute for Adult Diseases, Asahi Life Foundation, Tokyo, Japan

  http://orcid.org/0000-0001-8495-2073

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• Christine Le,

  Roles Data curation, Investigation, Methodology, Writing – review & editing

  Affiliation Department of Medicine, University of California, San Diego, La Jolla, California, United States of America

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• Jarosław Kalisiak,

  Roles Conceptualization, Investigation, Methodology, Writing – review & editing

  Affiliation Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, United States of America

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• Keith A. Korthals,

  Roles Conceptualization, Investigation, Methodology, Writing – review & editing

  Affiliation Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, United States of America

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• Majid Ghassemian,

  Roles Data curation, Investigation, Methodology, Software, Writing – review & editing

  Affiliation Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California, United States of America

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• Diane K. Smith,

  Roles Conceptualization, Formal analysis, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Department of Chemistry and Biochemistry, San Diego State University, San Diego, California, United States of America

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• K. Barry Sharpless,

  Roles Conceptualization, Funding acquisition, Resources, Supervision, Writing – review & editing

  Affiliation Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, United States of America

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• Valery V. Fokin,

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing

  Affiliation Department of Chemistry, Dornsife College of Letters, Arts and Sciences, University of Southern California, Los Angeles, California, United States of America

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• Lars Eckmann

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Project administration, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: leckmann@ucsd.edu

  Affiliation Department of Medicine, University of California, San Diego, La Jolla, California, United States of America

  http://orcid.org/0000-0002-7987-8742

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